Select Publications
Henn D, Zhao D**, Sivaraj D**, Trotsyuk A, Bonham CA, Fischer KS, Kehl T, Fehlmann T, Greco AH, Kussie HC, Moortgat Illouz SE, Padmanabhan J, Barrera JA, Kneser U, Lenhof HP, Januszyk M, Levi B, Keller A, Longaker MT, Chen K^, Qi LS^, Gurtner GC^. Cas9-mediated knockout of Ndrg2 enhances the regenerative potential of dendritic cells for wound healing. Nat Commun. 2023 Aug 7;14(1):4729. doi: 10.1038/s41467-023-40519-z. PMID: 37550295; PMCID: PMC10406832.
Jiang Y*, Trotsyuk AA*, Niu S*, Henn D, Chen K, Shih CC, Larson MR, Mermin-Bunnell AM, Mittal S, Lai JC, Saberi A, Beard E, Jing S, Zhong D, Steele SR, Sun K, Jain T, Zhao E, Neimeth CR, Viana WG, Tang J, Sivaraj D, Padmanabhan J, Rodrigues M, Perrault DP, Chattopadhyay A, Maan ZN, Leeolou MC, Bonham CA, Kwon SH, Kussie HC, Fischer KS, Gurusankar G, Liang K, Zhang K, Nag R, Snyder MP, Januszyk M, Gurtner GC^, Bao Z^. Wireless, closed-loop, smart bandage with integrated sensors and stimulators for advanced wound care and accelerated healing. Nat Biotechnol. 2023 May;41(5):652-662. doi: 10.1038/s41587-022-01528-3. Epub 2022 Nov 24. PMID: 36424488.
Chen K*, Kwon SH*, Henn D*, Kuehlmann BA, Tevlin R, Bonham CA, Griffin M, Trotsyuk AA, Borrelli MR, Noishiki C, Padmanabhan J, Barrera JA, Maan ZN, Dohi T, Mays CJ, Greco AH, Sivaraj D, Lin JQ, Fehlmann T, Mermin-Bunnell AM, Mittal S, Hu MS, Zamaleeva AI, Keller A, Rajadas J, Longaker MT, Januszyk M, Gurtner GC. Disrupting biological sensors of force promotes tissue regeneration in large organisms. Nat Commun. 2021 Sep 6;12(1):5256. doi: 10.1038/s41467-021-25410-z. PMID: 34489407; PMCID: PMC8421385.
Chen K*, Henn D*, Januszyk M*, Barrera JA, Noishiki C, Bonham CA, Griffin M, Tevlin R, Carlomagno T, Shannon T, Fehlmann T, Trotsyuk AA, Padmanabhan J, Sivaraj D, Perrault DP, Zamaleeva AI, Mays CJ, Greco AH, Kwon SH, Leeolou MC, Huskins SL, Steele SR, Fischer KS, Kussie HC, Mittal S, Mermin-Bunnell AM, Diaz Deleon NM, Lavin C, Keller A, Longaker MT, Gurtner GC. Disrupting mechanotransduction decreases fibrosis and contracture in split-thickness skin grafting. Sci Transl Med. 2022 May 18;14(645):eabj9152. doi: 10.1126/scitranslmed.abj9152. Epub 2022 May 18. PMID: 35584231.
Chen K, Vigliotti A, Bacca M, McMeeking RM, Deshpande VS, Holmes JW. Role of boundary conditions in determining cell alignment in response to stretch. Proc Natl Acad Sci U S A. 2018 Jan 30;115(5):986-991. PMID: 29343646
Longaker MT, Rohric RJ, Greenberg L, Furnas H, Wald R Bansal V, Seify H, Tran A, Weston J, Korman JM, Chan R, Kaufman D, Dev VR, Mele JA, Januszyk M, Cowley C, McLaughlin P, Beasley B, Gurtner GC. A Randomized Controlled Trial of the Embrace Advanced Scar Therapy Device to Reduce Incisional Scar Formation. Plast Reconstr Surg. 2014 Sep;134(3):536-46. PMID: 24804638
Gurtner GC, Werner S, Barrandon Y, Longaker MT. Wound Repair and Regeneration. Nature. 2008 May 15;453(7193):314-21. PMID: 18480812
*Read our new paper investigating the importance of mechanical signaling in the foreign body response to biomedical implants
Padmanabhan J*, Chen K*, Sivaraj D*, Henn D, Kuehlmann BA, Kussie HC, Zhao ET, Kahn A, Bonham CA, Dohi T, Beck TC, Trotsyuk AA, Stern-Buchbinder ZA, Than PA, Hosseini HS, Barrera JA, Magbual NJ, Leeolou MC, Fischer KS, Tigchelaar SS, Lin JQ, Perrault DP, Borrelli MR, Kwon SH, Maan ZN, Dunn JCY, Nazerali R, Januszyk M, Prantl L, Gurtner GC. Allometrically scaling tissue forces drive pathological foreign-body responses to implants via Rac2-activated myeloid cells. Nat Biomed Eng. 2023 Nov;7(11):1419-1436. doi: 10.1038/s41551-023-01091-5. Epub 2023 Sep 25. PMID: 37749310; PMCID: PMC10651488.
* = contributed equally as co-first authors
** = contributed equally as co-second authors
^ = contributed equally as co-senior authors
Recent Publications from the Gurtner Lab
Publications Archive
Padmanabhan J*, Chen K*, Sivaraj D*, Henn D, Kuehlmann BA, Kussie HC, Zhao ET, Kahn A, Bonham CA, Dohi T, Beck TC, Trotsyuk AA, Stern-Buchbinder ZA, Than PA, Hosseini HS, Barrera JA, Magbual NJ, Leeolou MC, Fischer KS, Tigchelaar SS, Lin JQ, Perrault DP, Borrelli MR, Kwon SH, Maan ZN, Dunn JCY, Nazerali R, Januszyk M, Prantl L, Gurtner GC. Allometrically scaling tissue forces drive pathological foreign-body responses to implants via Rac2-activated myeloid cells. Nat Biomed Eng. 2023 Nov;7(11):1419-1436. doi: 10.1038/s41551-023-01091-5. Epub 2023 Sep 25. PMID: 37749310; PMCID: PMC10651488.
Henn D, Zhao D**, Sivaraj D**, Trotsyuk A, Bonham CA, Fischer KS, Kehl T, Fehlmann T, Greco AH, Kussie HC, Moortgat Illouz SE, Padmanabhan J, Barrera JA, Kneser U, Lenhof HP, Januszyk M, Levi B, Keller A, Longaker MT, Chen K^, Qi LS^, Gurtner GC^. Cas9-mediated knockout of Ndrg2 enhances the regenerative potential of dendritic cells for wound healing. Nat Commun. 2023 Aug 7;14(1):4729. doi: 10.1038/s41467-023-40519-z. PMID: 37550295; PMCID: PMC10406832.
Henn D, Trotsyuk AA, Barrera JA, Sivaraj D, Chen K, Mittal S, Mermin-Bunnell AM, Chattopadhyay A, Larson MR, Kinney BM, Nachbar J, TerKonda SP, Reddy S, Jeffers L, Sacks JM, Gurtner GC. Robotics in Plastic Surgery: It's Here. Plast Reconstr Surg. 2023 Jul 1;152(1):239-249. doi: 10.1097/PRS.0000000000010270. Epub 2023 Jun 29. PMID: 37382921.
Nachbar JM, Kinney BM, Sacks JM, Gurtner GC, TerKonda SP, Reddy SK, Jeffers LL. Cybersecurity and Technical Patient Privacy Protection. Plast Reconstr Surg. 2023 May 22. doi: 10.1097/PRS.0000000000010740. Epub ahead of print. PMID: 37220229.
TerKonda SP, TerKonda AA, Sacks JM, Kinney BM, Gurtner GC, Nachbar JM, Reddy SK, Jeffers LL. Artificial Intelligence: Singularity Approaches. Plast Reconstr Surg. 2024 Jan 1;153(1):204e-217e. doi: 10.1097/PRS.0000000000010572. Epub 2023 Apr 20. PMID: 37075274.
Griffin MF, Talbott HE, Guardino NJ, Guo JL, Spielman AF, Chen K, Parker JBL, Mascharak S, Henn D, Liang N, King M, Cotterell AC, Bauer-Rowe KE, Abbas DB, Diaz Deleon NM, Sivaraj D, Fahy EJ, Downer M, Akras D, Berry C, Cook J, Quarto N, Klein OD, Lorenz HP, Gurtner GC, Januszyk M, Wan DC, Longaker MT. Piezo inhibition prevents and rescues scarring by targeting the adipocyte to fibroblast transition. bioRxiv [Preprint]. 2023 Apr 4:2023.04.03.535302. doi: 10.1101/2023.04.03.535302. PMID: 37066136; PMCID: PMC10103999.
Sivaraj D*, Noishiki C*, Kosaric N*, Kiwanuka H, Kussie HC, Henn D, Fischer KS, Trotsyuk AA, Greco AH, Kuehlmann BA, Quintero F, Leeolou MC, Granoski MB, Hostler AC, Hahn WW, Januszyk M, Murad F, Chen K^, Gurtner GC^. Nitric oxide-releasing gel accelerates healing in a diabetic murine splinted excisional wound model. Front Med (Lausanne). 2023 Mar 2;10:1060758. doi: 10.3389/fmed.2023.1060758. PMID: 36999070; PMCID: PMC10045479.
Barrera JA, Trotsyuk AA, Henn D, Sivaraj D, Chen K, Mittal S, Mermin-Bunnell AM, Larson MR, Padmanabhan J, Kinney B, Nachbar J, Sacks J, Terkonda SP, Jeffers L, Gurtner GC. Blockchain, Information Security, Control, and Integrity: Who Is in Charge? Plast Reconstr Surg. 2023 Oct 1;152(4):751e-758e. doi: 10.1097/PRS.0000000000010409. Epub 2023 Mar 15. PMID: 36917745.
Parker JB, Griffin MF, Downer MA, Akras D, Berry CE, Cotterell AC, Gurtner GC, Longaker MT, Wan DC. Chelating the valley of death: Deferoxamine's path from bench to wound clinic. Front Med (Lausanne). 2023 Feb 15;10:1015711. doi: 10.3389/fmed.2023.1015711. PMID: 36873870; PMCID: PMC9975168.
Fischer KS, Litmanovich B, Sivaraj D, Kussie HC, Hahn WW, Hostler AC, Chen K^, Gurtner GC^. Protocol for the Splinted, Human-like Excisional Wound Model in Mice. Bio Protoc. 2023 Feb 5;13(3):e4606. doi: 10.21769/BioProtoc.4606. PMID: 36816987; PMCID: PMC9909311.
Tevlin R, Griffin M, Chen K, Januszyk M, Guardino N, Spielman A, Walters S, Gold GE, Chan CKF, Gurtner GC, Wan DC, Longaker MT. Denervation during mandibular distraction osteogenesis results in impaired bone formation. Sci Rep. 2023 Feb 6;13(1):2097. doi: 10.1038/s41598-023-27921-9. PMID: 36747028; PMCID: PMC9902545.
Kuehlmann B, Bonham CA, Gurtner GC, Prantl L. Matrix Metalloproteinase-9 as a Potential Biomarker in 631 Human Implant-Induced Fibrotic Capsules: Analysis and Biomarker Study. Plast Reconstr Surg. 2023 Oct 1;152(4):637e-645e. doi: 10.1097/PRS.0000000000010262. Epub 2023 Feb 2. PMID: 36735824.
Sivaraj D, Fischer KS, Kim TS, Chen K, Tigchelaar SS, Trotsyuk AA, Gurtner GC, Lee GK, Henn D, Nazerali RS. Outcomes of Biosynthetic and Synthetic Mesh in Ventral Hernia Repair. Plast Reconstr Surg Glob Open. 2022 Dec 12;10(12):e4707. doi: 10.1097/GOX.0000000000004707. PMID: 36530858; PMCID: PMC9746774.
Januszyk M, Griffin M, Mascharak S, Talbott HE, Chen K, Henn D, Spielman AF, Parker JBL, Liang NE, Cotterell A, Guardino N, Foster DS, Wagh D, Coller J, Gurtner GC, Wan DC, Longaker MT. Multiplexed evaluation of mouse wound tissue using oligonucleotide barcoding with single-cell RNA sequencing. STAR Protoc. 2022 Dec 15;4(1):101946. doi: 10.1016/j.xpro.2022.101946. Epub ahead of print. PMID: 36525348; PMCID: PMC9792534.
Jiang Y*, Trotsyuk AA*, Niu S*, Henn D, Chen K, Shih CC, Larson MR, Mermin-Bunnell AM, Mittal S, Lai JC, Saberi A, Beard E, Jing S, Zhong D, Steele SR, Sun K, Jain T, Zhao E, Neimeth CR, Viana WG, Tang J, Sivaraj D, Padmanabhan J, Rodrigues M, Perrault DP, Chattopadhyay A, Maan ZN, Leeolou MC, Bonham CA, Kwon SH, Kussie HC, Fischer KS, Gurusankar G, Liang K, Zhang K, Nag R, Snyder MP, Januszyk M, Gurtner GC^, Bao Z^. Wireless, closed-loop, smart bandage with integrated sensors and stimulators for advanced wound care and accelerated healing. Nat Biotechnol. 2022 Nov 24. doi: 10.1038/s41587-022-01528-3. Epub ahead of print. PMID: 36424488.
Foster DS, Januszyk M, Delitto D, Yost KE, Griffin M, Guo J, Guardino N, Delitto AE, Chinta M, Burcham AR, Nguyen AT, Bauer-Rowe KE, Titan AL, Salhotra A, Jones RE, da Silva O, Lindsay HG, Berry CE, Chen K, Henn D, Mascharak S, Talbott HE, Kim A, Nosrati F, Sivaraj D, Ransom RC, Matthews M, Khan A, Wagh D, Coller J, Gurtner GC, Wan DC, Wapnir IL, Chang HY, Norton JA, Longaker MT. Multiomic analysis reveals conservation of cancer-associated fibroblast phenotypes across species and tissue of origin. Cancer Cell. 2022 Nov 14;40(11):1392-1406.e7. doi: 10.1016/j.ccell.2022.09.015. Epub 2022 Oct 20. PMID: 36270275; PMCID: PMC9669239.
Bauer CJ, Findlay M, Koliamitra C, Zimmer P, Schick V, Ludwig S, Gurtner GC, Riedel B, Schier R. Preoperative exercise induces endothelial progenitor cell mobilisation in patients undergoing major surgery - A prospective randomised controlled clinical proof-of-concept trial. Heliyon. 2022 Sep 23;8(9):e10705. doi: 10.1016/j.heliyon.2022.e10705. PMID: 36200018; PMCID: PMC9529507.
Padmanabhan J, Liu FC, Sivaraj D, Henn D, Chen K, Simon DR, Barrera JA, Gurtner GC. Two Independent Capsules Surrounding a Single Textured Implant in Ehlers-Danlos Syndrome. Plast Reconstr Surg Glob Open. 2022 Aug 25;10(8):e4470. doi: 10.1097/GOX.0000000000004470. PMID: 36032379; PMCID: PMC9410635.
Chen K, Henn D, Gurtner GC. Holy grail of tissue regeneration: Size. Bioessays. 2022 Sep;44(9):e2200047. doi: 10.1002/bies.202200047. Epub 2022 Jul 14. PMID: 35835730.
Lintel H, Abbas DB, Lavin CV, Griffin M, Guo JL, Guardino N, Churukian A, Gurtner GC, Momeni A, Longaker MT, Wan DC. Transdermal deferoxamine administration improves excisional wound healing in chronically irradiated murine skin. J Transl Med. 2022 Jun 17;20(1):274. doi: 10.1186/s12967-022-03479-4. PMID: 35715816; PMCID: PMC9205074.
Chen K*, Henn D*, Januszyk M*, Barrera JA, Noishiki C, Bonham CA, Griffin M, Tevlin R, Carlomagno T, Shannon T, Fehlmann T, Trotsyuk AA, Padmanabhan J, Sivaraj D, Perrault DP, Zamaleeva AI, Mays CJ, Greco AH, Kwon SH, Leeolou MC, Huskins SL, Steele SR, Fischer KS, Kussie HC, Mittal S, Mermin-Bunnell AM, Diaz Deleon NM, Lavin C, Keller A, Longaker MT, Gurtner GC. Disrupting mechanotransduction decreases fibrosis and contracture in split-thickness skin grafting. Sci Transl Med. 2022 May 18;14(645):eabj9152. doi: 10.1126/scitranslmed.abj9152. Epub 2022 May 18. PMID: 35584231.
Boulton AJM, Armstrong DG, Löndahl M, Frykberg RG, Game FL, Edmonds ME, Orgill DP, Kramer K, Gurtner GC, Januszyk M, Vileikyte L. New Evidence-Based Therapies for Complex Diabetic Foot Wounds. Arlington (VA): American Diabetes Association; 2022 May. PMID: 35763580.
Perrault DP, Sharma A, Kim JF, Gurtner GC, Wan DC. Surgical Applications of Materials Engineered with Antimicrobial Properties. Bioengineering (Basel). 2022 Mar 26;9(4):138. doi: 10.3390/bioengineering9040138. PMID: 35447700; PMCID: PMC9030825.
Chen K*, Sivaraj D*, Davitt MF, Leeolou MC, Henn D, Steele SR, Huskins SL, Trotsyuk AA, Kussie HC, Greco AH, Padmanabhan J, Perrault DP, Zamaleeva AI, Longaker MT, Gurtner GC. Pullulan-Collagen hydrogel wound dressing promotes dermal remodelling and wound healing compared to commercially available collagen dressings. Wound Repair Regen. 2022 May;30(3):397-408. doi: 10.1111/wrr.13012. Epub 2022 Apr 18. PMID: 35384131; PMCID: PMC9321852.
Jiang Y, Zhang Z, Wang YX, Li D, Coen CT, Hwaun E, Chen G, Wu HC, Zhong D, Niu S, Wang W, Saberi A, Lai JC, Wu Y, Wang Y, Trotsyuk AA, Loh KY, Shih CC, Xu W, Liang K, Zhang K, Bai Y, Gurusankar G, Hu W, Jia W, Cheng Z, Dauskardt RH, Gurtner GC, Tok JB, Deisseroth K, Soltesz I, Bao Z. Topological supramolecular network enabled high-conductivity, stretchable organic bioelectronics. Science. 2022 Mar 25;375(6587):1411-1417. doi: 10.1126/science.abj7564. Epub 2022 Mar 24. PMID: 35324282.
Henn D, Barrera JA, Sivaraj D, Lin JQ, Rizk NM, Ma I, Gurtner GC, Lee GK, Nazerali RS. Combining Breast and Ovarian Operations Increases Complications. Plast Reconstr Surg. 2022 May 1;149(5):1050-1059. doi: 10.1097/PRS.0000000000008984. Epub 2022 Mar 2. PMID: 35245249.
Henn D, Fischer KS, Chen K, Greco AH, Martin RA, Sivaraj D, Trotsyuk AA, Mao HQ, Reddy SK, Kneser U, Gurtner GC, Schmidt VJ, Sacks JM. Enrichment of Nanofiber Hydrogel Composite with Fractionated Fat Promotes Regenerative Macrophage Polarization and Vascularization for Soft-Tissue Engineering. Plast Reconstr Surg. 2022 Mar 1;149(3):433e-444e. doi: 10.1097/PRS.0000000000008872. PMID: 35196680.
Sivaraj D, Henn D, Fischer KS, Kim TS, Black CK, Lin JQ, Barrera JA, Leeolou MC, Makarewicz NS, Chen K, Perrault DP, Gurtner GC, Lee GK, Nazerali R. Reinforced Biologic Mesh Reduces Postoperative Complications Compared to Biologic Mesh after Ventral Hernia Repair. Plast Reconstr Surg Glob Open. 2022 Feb 7;10(2):e4083. doi: 10.1097/GOX.0000000000004083. PMID: 35141102; PMCID: PMC8820910.
Eriksson E, Liu PY, Schultz GS, Martins-Green MM, Tanaka R, Weir D, Gould LJ, Armstrong DG, Gibbons GW, Wolcott R, Olutoye OO, Kirsner RS, Gurtner GC. Chronic wounds: Treatment consensus. Wound Repair Regen. 2022 Mar;30(2):156-171. doi: 10.1111/wrr.12994. Epub 2022 Feb 7. Erratum in: Wound Repair Regen. 2022 Jul;30(4):536. PMID: 35130362; PMCID: PMC9305950.
Mascharak S, Talbott HE, Januszyk M, Griffin M, Chen K, Davitt MF, Demeter J, Henn D, Bonham CA, Foster DS, Mooney N, Cheng R, Jackson PK, Wan DC, Gurtner GC, Longaker MT. Multi-omic analysis reveals divergent molecular events in scarring and regenerative wound healing. Cell Stem Cell. 2022 Feb 3;29(2):315-327.e6. doi: 10.1016/j.stem.2021.12.011. Epub 2022 Jan 24. PMID: 35077667; PMCID: PMC8988390.
Davis MR, Gurtner GC, Eriksson E. Wound care research sponsored by the Department of Defense. Wound Repair Regen. 2022 Mar;30(2):151-155. doi: 10.1111/wrr.12993. Epub 2022 Jan 25. PMID: 35076141.
Sivaraj D, Padmanabhan J, Chen K, Henn D, Noishiki C, Trotsyuk AA, Kussie HC, Leeolou MC, Magbual NJ, Andrikopoulos S, Perrault DP, Barrera JA, Januszyk M, Gurtner GC. IQGAP1-mediated mechanical signaling promotes the foreign body response to biomedical implants. FASEB J. 2022 Feb;36(2):e22007. doi: 10.1096/fj.202101354. PMID: 35051300.
Hajhosseini B, Gurtner GC. Reply: Hyperbaric Oxygen Therapy in Management of Diabetic Foot Ulcers: Indocyanine Green Angiography May Be Used as a Biomarker to Analyze Perfusion and Predict Response to Treatment. Plast Reconstr Surg. 2022 Feb 1;149(2):347e. doi: 10.1097/PRS.0000000000008759. PMID: 34965241.
Than PA, Davis CR, Rennert RC, Morrison SD, Findlay MW, Kay MA, Gurtner GC. Selective Microvascular Tissue Transfection Using Minicircle DNA for Systemic Delivery of Human Coagulation Factor IX in a Rat Model Using a Therapeutic Flap. Plast Reconstr Surg. 2022 Jan 1;149(1):117-129. doi: 10.1097/PRS.0000000000008630. PMID: 34757962.
Dip F, Boni L, Bouvet M, Carus T, Diana M, Falco J, Gurtner GC, Ishizawa T, Kokudo N, Lo Menzo E, Low PS, Masia J, Muehrcke D, Papay FA, Pulitano C, Schneider-Koraith S, Sherwinter D, Spinoglio G, Stassen L, Urano Y, Vahrmeijer A, Vibert E, Warram J, Wexner SD, White K, Rosenthal RJ. Consensus Conference Statement on the General Use of Near-infrared Fluorescence Imaging and Indocyanine Green Guided Surgery: Results of a Modified Delphi Study. Ann Surg. 2022 Apr 1;275(4):685-691. doi: 10.1097/SLA.0000000000004412. PMID: 33214476; PMCID: PMC8906245.
Henn D, Chen K, Fehlmann T, Trotsyuk AA, Sivaraj D, Maan ZN, Bonham CA Jr, Barrera JA, Mays CJ, Greco AH, Moortgat Illouz SE, Lin JQ, Steele SR, Foster DS, Padmanabhan J, Momeni A, Nguyen D, Wan DC, Kneser U, Januszyk M, Keller A, Longaker MT, Gurtner GC. Xenogeneic skin transplantation promotes angiogenesis and tissue regeneration through activated Trem2+ macrophages. Sci Adv. 2021 Dec 3;7(49):eabi4528. doi: 10.1126/sciadv.abi4528. Epub 2021 Dec 1. PMID: 34851663; PMCID: PMC8635426.
Leeolou MC, Perrault DP, Sivaraj D, Chang ALS, Chen K, Trotsyuk AA, Padmanabhan J, Gurtner GC. A rare case of Wohlfahrtiimonas chitiniclastica infection in California. JAAD Case Rep. 2021 Sep 30;17:55-57. doi: 10.1016/j.jdcr.2021.09.022. PMID: 34703866; PMCID: PMC8526914.
Henn D, Sivaraj D, Barrera JA, Lin JQ, Chattopadhyay A, Maan ZN, Chen K, Nguyen A, Cheesborough J, Gurtner GC, Lee GK, Nazerali R. The Plane of Mesh Placement Does Not Impact Abdominal Donor Site Complications in Microsurgical Breast Reconstruction. Ann Plast Surg. 2021 Nov 1;87(5):542-546. doi: 10.1097/SAP.0000000000002897. PMID: 34699433.
Hajhosseini B, Gurtner GC. Reply: Hyperbaric Oxygen Therapy in Management of Diabetic Foot Ulcers: Indocyanine Green Angiography May Be Used as a Biomarker to Analyze Perfusion and Predict Response to Treatment. Plast Reconstr Surg. 2021 Dec 1;148(6):1065e-1066e. doi: 10.1097/PRS.0000000000008553. PMID: 34665795.
Foster DS, Januszyk M, Yost KE, Chinta MS, Gulati GS, Nguyen AT, Burcham AR, Salhotra A, Ransom RC, Henn D, Chen K, Mascharak S, Tolentino K, Titan AL, Jones RE, da Silva O, Leavitt WT, Marshall CD, des Jardins-Park HE, Hu MS, Wan DC, Wernig G, Wagh D, Coller J, Norton JA, Gurtner GC, Newman AM, Chang HY, Longaker MT. Integrated spatial multiomics reveals fibroblast fate during tissue repair. Proc Natl Acad Sci U S A. 2021 Oct 12;118(41):e2110025118. doi: 10.1073/pnas.2110025118. PMID: 34620713; PMCID: PMC8521719.
Lavin CV, Abbas DB, Fahy EJ, Lee DK, Griffin M, Diaz Deleon NM, Mascharak S, Chen K, Momeni A, Gurtner GC, Longaker MT, Wan DC. A comparative analysis of deferoxamine treatment modalities for dermal radiation-induced fibrosis. J Cell Mol Med. 2021 Nov;25(21):10028-10038. doi: 10.1111/jcmm.16913. Epub 2021 Oct 6. PMID: 34612609; PMCID: PMC8572785.
Maan ZN, Rinkevich Y, Barrera J, Chen K, Henn D, Foster D, Bonham CA, Padmanabhan J, Sivaraj D, Duscher D, Hu M, Yan K, Januszyk M, Longaker MT, Weissman IL, Gurtner GC. Epidermal-Derived Hedgehog Signaling Drives Mesenchymal Proliferation during Digit Tip Regeneration. J Clin Med. 2021 Sep 20;10(18):4261. doi: 10.3390/jcm10184261. PMID: 34575372; PMCID: PMC8467649.
Januszyk M, desJardins-Park HE, Gurtner GC, Longaker MT. Discussion: Overcoming the Patent Gap: A Guide to Patenting for Plastic Surgeons. Plast Reconstr Surg. 2021 Oct 1;148(4):918-919. doi: 10.1097/PRS.0000000000008394. PMID: 34550949.
Trotsyuk AA, Chen K, Hyung S, Ma KC, Henn D, Mermin-Bunnell AM, Mittal S, Padmanabhan J, Larson MR, Steele SR, Sivaraj D, Bonham CA, Noishiki C, Rodrigues M, Jiang Y, Jing S, Niu S, Chattopadhyay A, Perrault DP, Leeolou MC, Fischer KS, Gurusankar G, Choi Kussie H, Wan DC, Januszyk M, Longaker MT, Gurtner GC. Inhibiting Fibroblast Mechanotransduction Modulates Severity of Idiopathic Pulmonary Fibrosis. Adv Wound Care (New Rochelle). 2022 Oct;11(10):511-523. doi: 10.1089/wound.2021.0077. Epub 2021 Nov 30. PMID: 34544267.
desJardins-Park HE, Gurtner GC, Wan DC, Longaker MT. From Chronic Wounds to Scarring: The Growing Health Care Burden of Under- and Over-Healing Wounds. Adv Wound Care (New Rochelle). 2022 Sep;11(9):496-510. doi: 10.1089/wound.2021.0039. Epub 2021 Nov 15. PMID: 34521257.
Griffin MF, Borrelli MR, Garcia JT, Januszyk M, King M, Lerbs T, Cui L, Moore AL, Shen AH, Mascharak S, Diaz Deleon NM, Adem S, Taylor WL, desJardins- Park HE, Gastou M, Patel RA, Duoto BA, Sokol J, Wei Y, Foster D, Chen K, Wan DC, Gurtner GC, Lorenz HP, Chang HY, Wernig G, Longaker MT. JUN promotes hypertrophic skin scarring via CD36 in preclinical in vitro and in vivo models. Sci Transl Med. 2021 Sep;13(609):eabb3312. doi: 10.1126/scitranslmed.abb3312. Epub 2021 Sep 1. PMID: 34516825; PMCID: PMC8988368.
Chen K, Kwon SH, Henn D, Kuehlmann BA, Tevlin R, Bonham CA, Griffin M, Trotsyuk AA, Borrelli MR, Noishiki C, Padmanabhan J, Barrera JA, Maan ZN, Dohi T, Mays CJ, Greco AH, Sivaraj D, Lin JQ, Fehlmann T, Mermin-Bunnell AM, Mittal S, Hu MS, Zamaleeva AI, Keller A, Rajadas J, Longaker MT, Januszyk M, Gurtner GC. Disrupting biological sensors of force promotes tissue regeneration in large organisms. Nat Commun. 2021 Sep 6;12(1):5256. doi: 10.1038/s41467-021-25410-z. PMID: 34489407; PMCID: PMC8421385.
Abbas DB, Lavin CV, Fahy EJ, Griffin M, Guardino N, King M, Chen K, Lorenz PH, Gurtner GC, Longaker MT, Momeni A, Wan DC. Standardizing Dimensionless Cutometer Parameters to Determine In Vivo Elasticity of Human Skin. Adv Wound Care (New Rochelle). 2022 Jun;11(6):297-310. doi: 10.1089/wound.2021.0082. Epub 2021 Oct 8. PMID: 34470542; PMCID: PMC8982109.
Mascharak S, desJardins-Park HE, Davitt MF, Guardino NJ, Gurtner GC, Wan DC, Longaker MT. Modulating Cellular Responses to Mechanical Forces to Promote Wound Regeneration. Adv Wound Care (New Rochelle). 2022 Sep;11(9):479-495. doi: 10.1089/wound.2021.0040. Epub 2021 Oct 8. PMID: 34465219; PMCID: PMC9245727.
Chen K, Henn D, Sivaraj D, Bonham CA, Griffin M, Kussie HC, Padmanabhan J, Trotsyuk AA, Wan DC, Januszyk M, Longaker MT, Gurtner GC. Mechanical Strain Drives Myeloid Cell Differentiation Toward Proinflammatory Subpopulations. Adv Wound Care (New Rochelle). 2022 Sep;11(9):466-478. doi: 10.1089/wound.2021.0036. Epub 2021 Aug 27. PMID: 34278820.
Miller TJ, Remington AC, Nguyen DH, Gurtner GC, Momeni A. Preoperative β-lactam antibiotic prophylaxis is superior to bacteriostatic alternatives in immediate expander-based breast reconstruction. J Surg Oncol. 2021 Oct;124(5):722-730. doi: 10.1002/jso.26599. Epub 2021 Jul 8. PMID: 34235740; PMCID: PMC8429203.
Sivaraj D, Chen K, Chattopadhyay A, Henn D, Wu W, Noishiki C, Magbual NJ, Mittal S, Mermin-Bunnell AM, Bonham CA, Trotsyuk AA, Barrera JA, Padmanabhan J, Januszyk M, Gurtner GC. Hydrogel Scaffolds to Deliver Cell Therapies for Wound Healing. Front Bioeng Biotechnol. 2021 May 3;9:660145. doi: 10.3389/fbioe.2021.660145. PMID: 34012956; PMCID: PMC8126987.
Mascharak S, desJardins-Park HE, Davitt MF, Griffin M, Borrelli MR, Moore AL, Chen K, Duoto B, Chinta M, Foster DS, Shen AH, Januszyk M, Kwon SH, Wernig G, Wan DC, Lorenz HP, Gurtner GC, Longaker MT. Preventing Engrailed-1 activation in fibroblasts yields wound regeneration without scarring. Science. 2021 Apr 23;372(6540):eaba2374. doi: 10.1126/science.aba2374. PMID: 33888614; PMCID: PMC9008875.
Barrera JA, Trotsyuk AA, Maan ZN, Bonham CA, Larson MR, Mittermiller PA, Henn D, Chen K, Mays CJ, Mittal S, Mermin-Bunnell AM, Sivaraj D, Jing S, Rodrigues M, Kwon SH, Noishiki C, Padmanabhan J, Jiang Y, Niu S, Inayathullah M, Rajadas J, Januszyk M, Gurtner GC. Adipose-Derived Stromal Cells Seeded in Pullulan-Collagen Hydrogels Improve Healing in Murine Burns. Tissue Eng Part A. 2021 Jun;27(11-12):844-856. doi: 10.1089/ten.TEA.2020.0320. Epub 2021 May 27. PMID: 33789446.
Titan AL, Fahy E, Chen K, Foster DS, Bennett-Kennett R, Dauskardt RH, Gurtner GC, Chang J, Fox PM, Longaker MT. Proceed with Caution: Mouse Deep Digit Flexor Tendon Injury Model. Plast Reconstr Surg Glob Open. 2021 Jan 26;9(1):e3359. doi: 10.1097/GOX.0000000000003359. PMID: 33552814; PMCID: PMC7859083.
Fu S, Panayi A, Fan J, Mayer HF, Daya M, Khouri RK, Gurtner GC, Ogawa R, Orgill DP. Mechanotransduction in Wound Healing: From the Cellular and Molecular Level to the Clinic. Adv Skin Wound Care. 2021 Feb 1;34(2):67-74. doi: 10.1097/01.ASW.0000725220.92976.a7. PMID: 33443911.
Hajhosseini B, Chiou GJ, Virk SS, Chandra V, Moshrefi S, Meyer S, Kamperman KJ, Gurtner GC. Hyperbaric Oxygen Therapy in Management of Diabetic Foot Ulcers: Indocyanine Green Angiography May Be Used as a Biomarker to Analyze Perfusion and Predict Response to Treatment. Plast Reconstr Surg. 2021 Jan 1;147(1):209-214. doi: 10.1097/PRS.0000000000007482. PMID: 33370067.
Dong Y, Cui M, Qu J, Wang X, Kwon SH, Barrera J, Elvassore N, Gurtner C. Conformable hyaluronic acid hydrogel delivers adipose-derived stem cells and promotes regeneration of burn injury. Acta Biomaterialia. 2020 May;108:56-66. PMID: 32251786
Henn D, Chen K, Fischer K, Rauh A, Barrera J, Kim Y, Martin RA, Hannig M, Niedoba P, Reddy SK, Mao H, Kneser U, Gurtner GC, Sacks JM, Schmidt VJ. Tissue Engineering of Axially Vascularized Soft-Tissue Flaps with a Poly-(ɛ-Caprolactone) Nanofiber-Hydrogel Composite. Advances in Wound Care. 2020 Jan 14.
Rubin JP, Gurtner GC, Liu W, March KL, Seppanen-Kaijansinkko, Yaszemski MJ, Yoo JJ. Tissue Engineering Clinical Council Roundtable Discussion: Opportunities and Challenges in Clinical Translation. Tissue Engineering Part A. 2020 Jan 23. PMID: 31977299
Hajhosseini B, Longaker MT, Gurtner GC. Pressure Injury. Ann Surg. 2020 Apr;271(4):671-679. PMID: 31460882
Hajhosseini B, Chiou GJ, Dori G, Fukaya E, Chandra V, Meyer S, Gurtner GC. Er:YAG Laser versus Sharp Debridement in Management of Chronic Wounds: Effects on Pain and Bacterial Load. Wound Repair Regeneration. 2020 Jan;28(1):118-125. PMID: 31587431
Gurtner GC, Garcia A, Bakewll K, Alarcon J. A retrospective matched‐cohort study of 3994 lower extremity wounds of multiple etiologies across 644 institutions comparing a bioactive human skin allograft, TheraSkin, plus standard of care, to standard of care alone. International Wound Journal. 2020 Feb;17(1):55-64. PMID: 31729833
Seago M, Shumaker PR, Spring LK, Alam M, Al-Niaimi F, Rox Anderson R, Artzi O, Bayat A, Cassuto D, Chan HH, Dierickx C, Donelan M, Gauglitz GG, Leo Goo B, Goodman GJ, Gurtner G, Haedersdal M, Krakowski AC, Manuskiatti W, Norbury WB, Ogawa R, Ozog DM, Paasch U, Victor Ross E, Tretti Clementoni M, Waibel J. Laser Treatment of Traumatic Scars and Contractures: 2020 International Consensus Recommendations. Lasers Surg Med. 2020 Feb;52(2):96-116. PMID: 31820478
Kuehlmann B, Bonham CB, Zucal I, Prantl L, Gurtner GC. Mechanotransduction in Wound Healing and Fibrosis. J Clin. Med. 2020 May 11;9(5),1423.
Kosaric N, Kiwanuka H. Gurtner, GC. Stem Cell Therapies for Wound Healing. Expert Opinion on Biological Therapy. 2019 Mar 13; 9(6):575-585. PMID: 30900481
Kuehlmann B, Wan D, Gurtner GC. Discussion: Recipient-Site Preconditioning with Deferoxamine Increases Fat-Graft Survival by Inducing VEGF and Neovascularization in a Rat Model. Plastic Recon Surgery. 2019 Oct; 44(4):630e–631e. PMID: 31568299
Padmanabhan J, Maan ZN, Kwon SH, Kosaraju R, Bonham CA, Gurtner GC. In Vivo Models for the Study of Fibrosis. Adv Wound Care. 2019 Nov 6;8(12):645-654. PMID: 31827979
Davis CR, Than PA, Khong SML, Rodrigues M, Findlay MW, Navarrete DJ, Ghali S, Vaidya JS, Gurtner GC. Therapeutic breast reconstruction using gene therapy delivered IFN-gamma immunotherapy. Mol Cancer Ther.2019 Oct 28. PMID: 31658961
Duscher D, Trotsyuk AA, Maan ZN, Kwon SH, Rodrigues M, Engel K, Stern-Buchbinder ZA, Bonham CA, Barrera J, Whittam AJ, Hu MS, Inayathullah M, Rajadas J, Gurtner GC. Optimization of transdermal deferoxamine leads to enhanced efficacy in healing skin wounds. J Control Release. 2019 Aug 28;308:232-239. PMID: 31299261
Dohi T, Padmanabhan J, Akaishi S, Than PA, Terashima M, Matsumoto NN, Ogawa R, Gurtner GC. The Interplay of Mechanical Stress, Strain, and Stiffness at the Keloid Periphery Correlates with Increased Caveolin-1/ROCK Signaling and Scar Progression. Plast Reconstr Surg. 2019 Jul;44(1):58e-67e. PMID: 31246819
Hu MS, Maan ZN, Leavitt T, Hong WX, Rennert RC, Marshall CD, Borrelli MR, Zhu TN, Esquivel M, Zimmermann A, McArdle A, Chung MT, Foster DS, Jones RE, Gurtner GC, Giaccia AJ, Lorenz HP, Weissman IL, Longaker MT. Wounds Inhibit Tumor Growth In Vivo. Ann Surg. 2019 Feb 27. PMID: 30829705
Kosaric N and Gurtner GC. Stem Cell Therapies for Wound Healing. Expert Opinion on Biological Therapy. 2019 Apr;19:6, 575-585. PMID: 30900481
Dallas A, Trotsyuk A, Ilves H, Bonham CA, Rodrigues M, Engel K, Barrera JA, Kosaric N, Stern-Buchbinder ZA, White A, Mandell KJ, Hammond P, Mansbridge JN, Jayasena S, Gurtner GC, Johnston BH. Acceleration of Diabetic Wound Healing with PHD2- and miR-210-targeting Oligonucleotides. Tissue Eng Part A. 2019 Jan 1; 25(1-2): 44–54. PMID: 29644938
Dohi T, Padmanabhan J, Akaishi S, Than PA, Terashima M, Matsumoto NN, Ogawa R, Gurtner GC. The interplay of mechanical stress, strain and stiffness at the keloid periphery correlates with increased Caveolin-1/ROCK signaling and scar progression. Plast Reconstr Surg. 2019 Jul;144(1):58e–67e. PMID: 31246819.
Chen K, Hu X, Blemker SS, Holmes JW. Multiscale computational model of Achilles tendon wound healing: Untangling the effects of repair and loading. PLoS Comput Biol. 2018 Dec 14;14(12):e1006652. PMID: 30550566
Sorice SC, Remington A, Nguyen DH, Wan DC, Gurtner GC, Momeni A. Pre-Pectoral Vs. Sub-Pectoral Breast Reconstruction-a Matched-Pair Analysis of Clinical Outcomes. Plast Reconstr Surg Glob Open. 2018 Sep;6(9 Suppl):201-202
Armstrong DG, Gurtner GC. A Histologically Hostile Environment made more hospitable? Nature Reviews Endocrinology. 2018 Sep;14 (9):511-512. 2018 PMID: 30054565
Whittam AJ, Maan ZN, Duscher D, Barrera JA, Hu MS, Fischer LH, Khong S, Kwon SH, Wong VW, Walmsley GG, Giacco F, Januszyk M, Brownlee M, Longaker MT, Gurtner GC. Small molecule inhibition of Dipeptidyl Peptidase-4 enhances bone marrow progenitor cell function and angiogenesis in diabetic wounds. Translational Medicine. 2018 Nov 7;144(1):58e–67e. PMID: 30452888
Ma K, Kwon SH, Padmanabhan J, Duscher D, Trotsyuk AA, Dong Y, Inayathullah M, Rajadas J, Gurtner GC. Controlled delivery of a focal adhesion kinase inhibitor results in accelerated wound closure with decreased scar formation. Journal of Investigative Dermatology. 2018 Nov;138(11):2452-2460. PMID: 29775632
Khong SM, Lee M, Kosaric N, Khong DM, Dong Y, Hopfner U, Aitzetmuller MM, Duscher D, Schafer R, and Gurtner, GC. Single-cell Transriptomics of Human Mesenchymal Stem Cells Reveal Age-related Cellular Subpopulation Depletion and Impaired Regenerative Function. Stem Cells. 2018 Nov 9;37: 240-246. PMID: 30412645
Dong Y, Rodrigues M, Kwon SH, Li X, A S, Brett EA, Elvassore N, Wang W, Gurtner, CG. Acceleration of diabetic wound regeneration using an in-situ-formed stem cell-based skin substitute. Advanced Healthcare Materials. 2018 Jul 3;7(17). PMID: 30004192
Bonham CA, Rodrigues M, Galvez M, Trotsyuk A, Stern‐Buchbinder Z, Inayathullah M, Rajadas J, Gurtner GC.Deferoxamine can prevent pressure ulcers and accelerate healing in aged mice. Wound Rep and Reg. 2018 Aug 28;26: 300-305. PMID: 30152571
Ko SH, Nauta AC, Morrison SD, Hu MS, Zimmermann AS, Chung MT, Glotzbach JP, Wong VW, Walmsley GG, Peter Lorenz H, Chan DA, Gurtner GC, Giaccia AJ, Longaker MT. PHD-2 Suppression in Mesenchymal Stromal Cells Enhances Wound Healing. Plast Reconstr Surg. 2018 Jan;141(1):55e-67e. PMID: 29280872
Hu MS, Borrelli MR, Januszyk M, Luan A, Malhotra S, Walmsley GG, Hong WX, Tevlin R, Gurtner GC, Longaker MT, Lorenz HP. Pathway Analysis of Gene Expression of E14 Versus E18 Fetal Fibroblasts. Adv Wound Care (New Rochelle). 2018 Jan 1;7(1):1-10. PMID: 29344429
Hu MS, Cheng J, Borrelli MR, Leavitt T, Walmsley GG, Zielins ER, Hong WX, Cheung ATM, Duscher D, Maan ZN, Irizarry DM, Stephan B, Parsa FD, Wan DC, Gurtner GC, Lorenz HP, Longaker MT. An Improved Humanized Mouse Model for Excisional Wound Healing Using Double Transgenic Mice. Adv Wound Care (New Rochelle). 2018 Jan 1;7(1):1-10. PMID: 29344429
Barnes LA, Marshall CD, Leavitt T, Hu MS, Moore AL, Gonzalez JG, Longaker MT, Gurtner GC. Mechanical Forces in Cutaneous Wound Healing: Emerging Therapies to Minimize Scar Formation. Adv Wound Care (New Rochelle). 2018 Feb 1;7(2):47-56. PMID: 29392093
Rodrigues M, Kosaric N, Bonham CA, Gurtner CG. Wound Healing: A Cellular Perspective. Physiological Reviews. 2018 Nov 26;9(1):665-706. PMID: 30475656
Barnes AL, Marshall CD, Leavitt T, Hu MS, Moore AL, Gonzalez JG, Longaker MT. Mechanical Forces in Cutaneous Wound Healing: Emerging Therapies to Minimize Scar Formation. Advances in Wound Care. 2018 February 1;7(2):47-56. PMID: 29392093
Liu W, Ma K, Kwon SH, Garg R, Patta YR, Fujiwara T, . The Abnormal Architecture of Healed Diabetic Ulcers is the Result of FAK Degradation by Calpain 1. J Invest Dermatol. 2017 Jan 9. PMID: 28082186
Tevlin R, Seo EY, Marecic O, McArdle ATong X, Zimdahl B, Malkovskiy A, Sinha R, Gulati G, Li X, Wearda T, Morganti R, Lopez M, Ransom RC, Duldulao CR, Rodrigues M, Nguyen A, Januszyk M, Maan Z, Paik K, Yapa KS, Rajadas J, Wan DC, , Snyder M, Beachy PA, Yang F, Goodman SB, Weissman IL, Chan CK, Longaker MT. Pharmacological Rescue of Diabetic Skeletal Stem Cell Niches. Sci Transl Med. 2017 Jan 11;9(373). PMID: 28077677
Leavitt T, Hu MS, Zielins ER, Barnes LA, Marshall CD, Wan DC, Lorenz HP , Longaker MT. Excess Dermal Tissue Remodeling In Vivo: Does It Settle? Plast Reconstr Surg. 2017 Feb;139(2):415e-424e. PMID: 28121870
Duscher D, Januszyk M, Maan ZN, Hu MS, Walmsley GG, Dong Y, Khong SM, Longaker MT, . Comparison of the Hydroxylase Inhibitor Dimethyloxalylglycine and the Iron Chelator Deferoxamine in Diabetic and Aged Wound Healing. Plast Reconstr Surg. 2017 Mar;139(3):695e-706e. PMID: 28234841
Brett E, Zielins E, Chin M, Januszyk M, Blackshear C, Findlay M, Momeni A, Gurtner GC, Longaker MT, Wan D. Isolation of CD248-Expressing Stromal Vascular Fraction for Targeted Improvement of Wound Healing. Wound Repair and Regeneration. 2017 May 2;. PMID: 28464475
Dong Y, Sigen A, Rodrigues M, Li X, Kwon SH, Kosaric N, Khong S, Gao YS, Wan W, . Injectable and Tunable Gelatin Hydrogels Enhance Stem Cell Retention and Improve Cutaneous Wound Healing. Advanced Functional Materials. 2017 May 3;24(4)
Brett E, Zielins ER, Chin M, Januszyk M, Blackshear CP, Findlay M, Momeni A, Gurtner GC, Longaker MT, Wan DC. Isolation of CD248-expressing stromal vascular fraction for targeted improvement of wound healing. Wound Repair Regen. 2017 May 2; 25(3):414-422. PMID: 28464475
Fujiwara T, Dohi T, Rustad KC, Kwon SH, Padmanabhan J, Whittam AJ, Suga H, Duscher D, Rodrigues M, Gurtner GC. Age-Associated Intracellular Superoxide Dismutaase Deficiency Potentiates Dermal Fibroblast Dysfunction During Wound Healing. Exp Dermatol. 2017 Jul 4. PMID: 28677217
Zenn M, Venturi M, Pittman T, Spear S, Gurtner GC, Robb G, Mesbahi A, Dayan J. Optimizing Outcomes of Pstmastectomy Breast Reconstruction with Acellular Dermal Matrix: A Review of Recent Clinical Data. Eplasty. 2017 Jun 12;17:e18. PMID: 28663773
Spring LK, Krakowski AC, Alam M, Bhatia A, Brauer J, Cohen J, Del Rosso JQ, Diaz L, Dover J, Eichenfield LF, Gurtner GC, Hanke CW, Jahnke MN, Kelly KM, Khetarpal S, Kinney MA, Levy ML, Leyden J, Longaker MT, Munavalli GS, Ozog DM, Prather H, Shumaker PR, Tanzi E, Torres A, Velez MW, Waldman AB, Yan AC, Zaenglein AL. Isotretinoin and Timing of Procedural Interventions: A Systematic Review With Consensus Recommendations. JAMA Dermatol. 2017 Aug 1;153(8):802-809. PMID: 28658462
Januszyk M, Kwon SH, Wong VW, Padmanabhan J, Maan ZN, Whittam AJ, Major MR, Gurtner GC. The Role of Focal Adhesion Kinase in Keratinocyte Fibrogenic Gene Expression. Int J Mol Sci. 2017 Sep 7;17:e18. PMID: 288880199
Hu MS, Walmsley GG, Barnes LA, Weiskopf K, Rennert RC, Duscher D, Januszyk M, Maan ZN, Hong WX, Cheung AT, Leavitt T, Marshall CD, Ransom RC, Malhotra S, Moore AL, Rajadas J, Lorenz HP, Weissman IL, Gurtner GC, Longaker MT. Delivery of monocyte lineage cells in a biomimetic scaffold enhances tissue repair. JCI Insight. 2017 Oct 5;2(19). PMID: 28978794
Ennis WJ, Hoffman RA, Gurtner GC, Kirsner RS, Gordon HM. Wound healing outcomes: Using big data and a modified intent-to-treat method as a metric for reporting healing rates. Wound Repair Regen. 2017 Aug;25(4):665-672. PMID: 28846162
Flacco J, Chung N, Blackshear CP, Irizarry D, Momeni A, Lee GK, Nguyen D, Gurtner GC, Longaker MT, Wan DC. Deferoxamine Preconditioning of Irradiated Tissue Improves Perfusion and Fat Graft Retention. Plast Reconstr Surg. 2017 Nov 8. PMID: 29135894
Gurtner GC, Padmanabhan J. Disease models: Method in the madness of fibrosis. Nat Materials. 2017 Nov. 24;16(12):1176-1177. PMID: 29170546
Kosaraju R, Rennert RC, Maan ZN, Duscher D, Barrera J, Whittam AJ, Januszyk M, Rajadas J, Rodrigues M, Gurtner GC. Adipose-Derived Stem Cell-Seeded Hydrogels Increase Endogenous Progenitor Cell Recruitment and Neovascularization in Wounds. Tissue Eng Part A. 2016 Feb;22(3-4):295-305. PMID: 26871860
Davis CR, Rappleye CT, Than PA, Rodrigues M, Findlay MW, Bishop SN, Whitmore AJ, Maan ZN, McGoldrick RB, Grobbelaar AO, Gurtner GC. Sutureless Microsurgical Anastomosis Using an Optimized Thermoreversible Intravascular Poloxamer Stent. Plast Reconstr Surg. 2016 Feb;137(2):546-56. PMID: 26818289
Fujiwara T, Duscher D, Kristine KC, Kosaraju R, Rodrigues M, Whittam AJ, Januszyk M, Maan ZN, Gurtner GC. Extracellular Superoxide Dismutase Deficiency Impairs Wound Healing in Advanced Age by Reducing Neovascularization and Fibroblast Function. Exp Dermatol. 2016 Feb 10(3):206-211 PMCID: PMC4998179 NIHMSID: NIHMS776177 doi: 10.1111/exd.12909
Walmsley GG, Maan ZN, Hu MS, Atashroo DA, Whittam AJ, Duscher D, Tevlin R, Marecic O, Lorenz HP, Gurtner GC, Longaker MT. Murine Dermal Fibroblast Isolation by FACS. J Vis Exp. 2016 Jan 7;(107). PMID: 26780559
Rubin JP, Gurtner GC, LiuW, March KL, Seppanen-Kaijansinkko Md nDds PhD R, Yaszemski MJ, Yoo JJ. Surgical Therapies and Tissue Engineering: At the Intersection Between Innovation and Regulation. Tissue Eng Part A. 2016 Mar;22(5-6):397-400. PMID: 26895615
Rennert RC, Schäfer R, Bliss T, Januszyk M, Sorkin M, Achrol AS, Rodrigues M, Maan ZN, Kluba T, Steinberg GK, Gurtner GC. High-Resolution Microfluidic Single-Cell Transcriptional Profiling Reveals Clinically Relevant Subtypes among Human Stem Cell Populations Commonly Utilized in Cell-Based Therapies. Front Neurol. 2016 Mar 22;7:41. PMID: 27047447
Rennert RC, Achrol AS, Januszyk M, Kahn SA, Liu TT, Liu Y, Sahoo D, Rodrigues M, Maan ZN, Wong VW, Cheshier SH, Chang SD, Steinberg GK, Harsh GR, Gurtner GC. Multiple Subsets of Brain Tumor Initiating Cells Coexist in Glioblastoma. Stem Cells. 2016 Jun;34(6):1702-7. PMID: 26991945
Bertoni DM, Nguyen D, Rochlin D, Hernandez-Boussard T, Meyer S, Choy N, Gurtner GC, Wapnir IL. Protecting Nipple Perfusion by Devascularization and Surgical Delay in Patients at Risk for Ischemic Complications During Nipple-Sparing Mastectomies. Ann Surg Oncol. 2016 Aug;23(8):2665-72. PMID: 27038458
Paik KJ, Maan ZN, Zielins ER, Duscher D, Whittam AJ, Morrison SD, Brett EA, Ransom RC, Hu MS, Wu JC, Gurtner GC, Longaker MT, Wan DC. Short Hairpin RNA Silencing of PHD-2 Improves Neovascularization and Functional Outcomes in Diabetic Wounds and Ischemic Limbs. PLoS One. 2016 Mar 11;11(3):e0150927. PMID: 26967994
Luan A, Duscher D, Whittam AJ, Paik KJ, Zielins ER, Brett EA, Atashroo DA, Hu MS, Lee GK, Gurtner GC, Longaker MT, Wan DC. Cell-Assisted Lipotransfer Improves Volume Retention in Irradiated Recipient Sites and Rescues Radiation-Induced Skin Changes. Stem Cells. 2016 Mar;34(3):668-73. PMID: 26661694
Duscher D, Luan A, Rennert R, Atashroo D, Maan Z, Brett E, Whittam A, Ho N, Lin M, Hu M, Walmsley G, Wenny R, Schmidt M, Schilling A, Machens H-G, Huemer G, Wan D, Longaker M, Gurtner GC. Suction Assisted Liposuction Does Not Impair the Regenerative Potential of Adipose Derived Stem Cells. J Transl Med. 2016 May 6;14(1):126. PMID: 27153799
164.Rennert RC, Januszyk M, Sorkin M, Rodrigues M, Maan ZN, Duscher D, Whittam AJ, Kosaraju R, Chung MT, Paik K, Li AY, Findlay M, Glotzbach JP, Butte AJ, . Microfluidic Single-Cell Transcriptional Analysis Rationally Identifies Novel Surface Marker Profiles to Enhance Cell-Based Therapies. National Commun. 2016 Jun 21;7:11945. PMID: 27324848
Gurtner GC, Chapman MA. Regenerative Medicine: Charting a New Course in Wound Healing. Adv Wound Care (New Rochelle). 2016 Jul 1;5(7);314-238. PMID: 27366592
Collins B. Williams JZ, Karu H, Hodde JP, Marin VA, Gurtner GC. Nipple Reconstruction with the Biodesign Nipple Reconstruction Cylinder: A Prospective Clinical Study. Plast Reconstr Surg. 2016 Aug 9;4(8):e832 PMID: 27622100
Kwon SH, Gurtner GC. Is Early Inflammation Good or Bad? Linking Early Immune Changes to Hypertrophic Scarring. Exp Dermatol. 2016 Aug 11. PMID: 27513689
Jothimuthu P, Hsu J, Chen R, Inayathullah M, Pothineni VR, Dhillon G, Gurtner GC, Rajadas J, Nicolls M. Electrochemical Lab-on-a-Chip Sensor (Ferrochip) Using Modified Carbon Nanotubes (CNTs) for Iron Detection. ChemNanoMat.2016 Sep;(2)9:904-910. PMID:27857882
Rodrigues M, Wong VW, Gurtner GC. Finding a Needle in a “Needlestack.” Cell Cycle. 2016 Aug 30:1-2. PMID: 27575400
Sorice S, Rustad KC, Li AY, Gurtner GC. The Role of Stem Cell Therapeutics in Wound Healing: Current Understanding and Future Directions. Plast Reconstr Surg. 2016 Sep;138(3 Suppl):31S-41S. PMID: 27556772
Robb GL, Gurtner GC. Healing Rates in a Multicenter Assessment of a Sterile, Room Temperature, Acellular Dermal Matrix Versus Conventional Care Wound Management and an Active Comparator in the Treatment of Full-Thickness Diabetic Foot Ulcers. Eplasty. 2016 Sep 7;16:e27. PMID: 27648117
Whittam AJ, Maan ZN, Duscher D, Wong VW, Barrera JA, Januszyk M, Gurtner GC. Challenges and Opportunities in Drug Delivery for Wound Healing. Adv Wound Care (New Rochelle). 2016 Feb 1;5(2):79-88. PMID: 26862465
Walmsley GG, Senarath-Yapa K, Wearda TL, Menon S, Hu MS, Duscher D, Maan ZM, Tsai JM, Zielins ER, Weissman IL, Gurtner GC, Lorenz HP, Longaker MT. Surveillance of Stem Cell Fate and Function: A System for Assessing Cell Survival and Collagen Expression In Situ. Tissue Eng Part A. 2016 Jan;22(1-2):31-40. PMID: 26486617
Rosenthal EL, Warram JM, de Boer E, Basilion JP, Biel MA, Bogyo M, Bouvet M, Brigman BE, Colson YL, DeMeester, SR Gurtner GC, Ishizawa T, Jacobs PM, Keereweer S, Liao JC, Nguyen QT, Olson JM Paulsen KD, Rieves D, Sumer BD, Tweedle MF, Vahrmeijer AL, Weichert JP, Wilson BC, Zenn MR, Zinn KR, van Dam GM. Successful Translation of Fluorescence Navigation During Oncologic Surgery: A Consensus Report. J Nucl Med. 2016 Jan;57(1):144-50. PMID: 26449839
Zielins ER, Paik K, Ranson RC, Brett EA, Blackshear C, Luan A, Walmsley GG, Atashroo DA, Senarath-Yapa K, Momeni A, Rennert RC, Sorkin M, Seo EY, Chan CK, Gurtner GC, Longaker Mt, Wan DC. Enrichment of Adipose Derived Stromal Cells for BMPR1A Facilitates Enhanced Adipogenesis. Tissue Eng Apart A. 2016 Feb;22(3-4):214-21. PMID: 26585335
Jung K, Covington S, Sen CK, Januszyk M, Kirsner RS, Gurtner GC, Shah NH. Rapid Identification of Slow Healing Wounds. Wound Repair Regen. 2016 Jan-Feb;24(1):181-8. PMID: 26606167
Luan A, Duscher D, Whittam AJ, Paik KJ, Zielins ER, Brett EA, Atashroo DA, Hu MS, Lee GK, Gurtner GC, Longaker MT, Wan DC. Cell-Assisted Lipotransfer Improves Volume Retention in Irradiated Recipient Sites and Rescues Radiation-Induced Skin Changes. Stem Cells. 2016 Mar;34(3):668-73. PMID: 26661694
Fujiwara T, Duscher D, Rustad KC, Kosaraju R, Rodrigues M, Whittam AJ, Januszyk M, Maan ZN, Gurtner GC. Extracellular Superoxide Dismutase Deficiency Imparis Wound Healing in Advanced Age by Reducing Neovascularizaiton and Fibroblast Function. Exp Dermatol. 2016 Mar;25(3):206-11. PMID: 26663425
Duscher D, Atashroo D, Maan ZN, Luan A, Brett EA, Barrera J, Khong SM, Zielins ER, Whittam AF, Hu MS, Walmsley GG, Pollhammer MS, Schmidt M, Schilling AF, Machens HG, Huemer Gm, Wan DC, Lonaker MT, Gurtner GC. Ultrasound-Assisted Liposuction Does Not Compromise the Regenerative Potential of Adipose-Derived Stem Cells. Stem Cells Transl Med. 2016 Feb;5(2):248-57. PMID 26702129
Duscher D, Barrera J, Wong VW, Maan ZN, Whittam AJ, Januszyk J, Gurtner GC. Stem Cells in Wound Healing: The Future of Regenerative Medicine? A Mini-Review. Gerontology. 2016;62(2):216-25. PMID: 26045256.
Walmsley GG, Maan ZN, Wong VW, Duscher D, Hu MS, Zielins ER, Wearda T, Muhonen E, McArdle A, Tevlin R, Atashroo D, Senarath-Yapa K, Lorenz HP, Gurtner GC, Longaker M. Scarless Wound Healing: Chasing the Holy Grail. Plast Reconstr Surg. 2015 Mar;135(3):907-17. PMID: 25719706
Paik KJ, Zielins ER, Atashroo DA, Maan ZN, Duscher D, Luan A, Walmsley GG, Momeni A, Vistnes S, Gurtner GC, Longaker MT, Wan DC. Studies in Fat Grafting: Part V. Cell-Assisted Lipotransfer to Enhance Fat Graft Retention is Dose Dependent. Plast Recon Surg. 2015 Jul;136(1):67-75. PMID: 25829158
Chang E, Paterno J, Duscher D, Maan Z, Chen J, Januszyk M, Rodrigues M, Rennert R, Bishop S, Whitmore AJ, Whittam A, Longaker MT, Gurtner GC. Exercise Induces Stromal Cell-Derived Factor-1a-Mediated Release of Endothelial Progenitor Cells with Increased Vasculogenic Function. Plast Reconstr Surg. 2015 Feb;135(2):340e-50e. PMID: 25626819
Walmsley GG, Rinkevich Y, Hu MS, Montoro DT, Lo DD, McArdle A, Maan Z, Morrison SD, Duscher D, Whittam AJ, Wong VW, Weissman IL, Gurtner G, Longaker M. Live Fibroblast Harvest Reveals Surface Marker Shift In Vitro. Tissue Eng Part C Methods. 2015 Mar;21(3):314-21. PMID: 25275778
Duscher D, Neosfartu E, Wong VW, Maan Z, Rennert RC, Inayathullah M, Januszyk M, Rodrigues M, Malkovskiy A, Whitmore AJ, Walmsley G, Galvez M, Whittam AJ, Brownlee M, Rajadas J, Gurtner GC. Transdermal Deferoxamine Prevents Pressure-Induced Diabetic Ulcers. Proc Natl Acad Sci U S A. 2015 Jan 6;112(1):94-9. PMID: 25535360
Zielins ER, Atashroo DA, Maan ZN, Duscher D, Walmsley GG, Hu M, Senarath-Yapa K, McArdle A, Tevlin R, Wearda T, Paik KJ, Duldulao C, Hong WX, Gurtner GC, Longaker MT. Wound Healing: An Update. Regen Med. 2014;9(6):817-30. PMID: 25431917
Major MR, Wong VW, Nelson ER, Longaker MT, Gurtner GC. The Foreign Body Response: At the Interface of Surgery and Bioengineering. Plast Reconstr Surg. 2015 May;135(5):1489-98. PMID: 25919260
Rinkevich Y, Walmsley GG, Hu MS, Maan ZN, Newman AM, Drukker M, Januszyk M, Krampitz GW, Gurtner CG, Lorenz HP, Weissman IL, Longaker MT. Skin Fibrosis. Identification and Isolation of a Dermal Lineage with Intrinsic Fibrogenic Potential. Science. 2015 Apr 17;348(6232)aaa2151. PMID: 25883361
Gurtner GC. Discussion: No Efficacy for Silicone Gel Sheeting in Prevention of Abnormal Scar Formation in Children with Cancer: A Randomized Controlled Trial. Plast Reconstr Surg. 2015 Apr;135(4):1095-6. PMID: 25811574
Tevlin R, Atashroo D, Duscher D, Mc Ardle A, Gurtner GC, Wan DC, Longaker MT. Impact of Surgical Innovation on Tissue Repair in the Surgical Patient. Br J Surg. 2015 Jan;102(2):e41-55. PMID: 25627135
Wan DC, Gurtner GC, Longaker MT. Reply: Studies in Fat Grafting: Part I. Effects of Injection Technique on In Vitro Fat Viability and In Vivo Volume Retention; and Studies in Fat Grafting: part II. Effects of Injection Mechanics on Material Properties of Fat. Plast Reconstr Surg. 2015 February;135(2):448e-9e. PMID: 25626833
Garza RM, Rennert RC, Paik KJ, Atashroo D, Chung MT, Duscher D, Januszyk M, Longaker MT, Wan DC. Studies in Fat Grafting: Part IV. Adipose-Derived Stromal Cell Gene Expression in Cell-Assisted Lipotransfer. Plastic Reconstr Surg. 2015 Apr;135(4):1045-55. PMID: 25502860
Walmsley GG, Atashroo DA, Maan ZN, Hu MS, Zielins ER, Tsai JM, Duscher D, Paik K, Tevlin R, Marecic O, Wan DC, Gurtner GC, Longaker MT. High-Throughput Screening of Surface Marker Expression on Undifferentiated and Differntiated Human Adipose-Derived Stromal Cells. Tissue Eng Part A. 2015 Aug;21(15-16):2281-91. PMID: 26020286
Dua MM, Bertoni DM, Nguyen D, Meyer S, Gurtner GC, Wapnir NL. Using Intraoperative Laser Angiography to Safeguard Nipple Perfusion in Nipple-Sparing Mastectomies. Gland Surg. 2015 Dec;4(6):497-505. PMID: 26645004
Tevlin R, Young Seo E, Marecic O, Wearda T, Mc Ardle A, Januszyk M, Gulati G, Maan Z, Hu MS, Walmsley GG, Gurtner GC, Chan CK, Weissman IL, Longaker MT. Skeletal Stem Cell Niche Aberrancies Underlie Impaired Fracture Healing in a Mouse Model of Type 2 Diabetes Is Driven By Skeletal Stem Cell Niche Dysregulation. Plast Reconstr Surg. 2015 Oct;136(4 Suppl):73. PMID: 26397581
Rodrigues M, Wong VW, Rennert RC, Davis CR, Longaker MT, Gurtner GC. Progenitor Cell Dysfunctions Underlie Some Diabetic Complications. Am J Pathol. 2015 Oct;185(10):2607-18. PMID: 26079815
Duscher D, Maan ZN, Whittam AJ, Sorkin M, Hu MS, Walmsley GG, Baker H, Fischer LH, Januszyk M, Wong VW, Gurtner GC. Fibrobast-Specific Deletion of Hypoxia Inducible Factor-1 Critically Impairs Murine Cutaneous Neovascularization and Wound Healing. Plast Reconstr Surg. 2015 Nov;136(5):1004-13. PMID:26505703
Gurtner GC, Wong VW. Filamin A Mediates Wound Closure by Promoting Elastic Deformation and Maintenance of Tension in the Collagen Matrix. J Invest Dermatol. 2015 Nov;135(11):2269-71. PMID: 26548489
Januszyk M, Sorkin M, Glotzbach J, Vial I, Maan Z, Rennert R, Duscher D, Thangarajah H, Longaker M, Butte A, Gurtner GC. Diabetes Irreversibly Depletes Bone Marrow-Derived Mesenchymal Progenitor Cell Subpopulations. Diabetes. Diabetes. 2014 Sep;63(9):3047-56. PMID: 24740572
Zimmermann A, Morrison Shane, Hu Michael, Li Shuli, Nauta A, Meyer Paul, Walmsley G, Maan Z, Chan D, Gurtner GC, Giaccia Amato J, Longaker MT. Epidermal or Dermal Specific Knockout of PHD-2 Enhances Wound Healing and Minimizes Ischemic Injury. Plos One. 2014 Apr 2;9(4):e93373. PMID: 24695462
Januszyk M, Wong VW, Bhatt KA, Vial N, Paterno J, Longaker M, Gurtner GC. Mechanical Offloading of Incisional Wounds is Associated with Transcriptional Downregulation of Inflammatory Pathways in a Large Animal Model. Organogenesis. 2014 Apr-Jun;10(2):186-93. PMID: 24739276
McArdle A, Senarth-Yapa, Walmsley GG, Hu M, Atashroo DA, Tevlin R, Zielins E, Gurtner GC, Wan DC, Longaker MT. The Role of Stem Cells in Aesthetic Surgery: Fact or Fiction? Plast Reconstr Surg. 2014 Aug;134(2):193-200. PMID 24732654
Suga H, Rennert RC, Rodrigues M, Sorkin M, Glotzbach JP, Januszyk M, Fujiwara T, Longaker MT, Gurtner GC. Tracking the Elusive Fibrocyte: Identification and Characterization of Collagen-Producing Hematopoietic Lineage Cells during Murine Wound Healing. Stem Cells. 2014 May;32(5):1347-60. PMID: 24446236
Satterwhite T, Son J, Carey J, Echo A, Spurling T, Paro J, Gurtner GC, Chang J, Lee GK. The Stanford Microsurgery And Resident Training (SMaRT) Scale: Validation of an On-Line Global Rating Scale for Technical Assessment. Ann Plast Surg. 2014 May;72 Supp 1:S84-8. PMID: 24691332.
Rennert RC, Rustad K, Levi K, Harwood M, Sorkin M, Wong VW, Al-Ahmad A, Zei P, Hsia H, Beygui R, Norton L, Wang, Gurtner GC. A Histological and Mechanical Analysis of the Cardiac Lead-Tissue Interface: Implications for Lead Extraction. Acta Biomater. 2014 May;10(5):2200-8. PMID: 24434537
Koob T, Lim JJ, Massee M, Zabek N, Rennert R, Gurtner GC, Li WW. Angiogenic Properties of Deyhdrated Human Amnion/Chorion Allografts: Theraputic Potential for Soft Tissue Repair and Regeneration. Vasc Cell.2014 1;6:10. PMID: 24817999
Longaker MT, Rohric RJ, Greenberg L, Furnas H, Wald R Bansal V, Seify H, Tran A, Weston J, Korman JM, Chan R, Kaufman D, Dev VR, Mele JA, Januszyk M, Cowley C, McLaughlin P, Beasley B, Gurtner GC. A Randomized Controlled Trial of the Embrace Advanced Scar Therapy Device to Reduce Incisional Scar Formation. Plast Reconstr Surg. 2014 Sep;134(3):536-46. PMID: 24804638
Hong WX, Hu MS, Rennert RC, McArdle A, Paik K, Duscher D, Gurtner GC, Giaccia A, Longaker MT. The Role of Hypoxia-Inducible Factor in Wound Healing. Adv Wound Care (New Rochelle). 2014 May;3(5):390-9. PMID: 24804159
Duscher D, Maan ZN, Wong VW, Rennert RC, Januszyk M, Rodrigues M, Hu M, Whitmore AJ, Whittam AJ, Longaker MT, Gurtner GC. Mechanotransduction and Fibrosis. J Biomech. 2014 Jun 27;47(9):1997-2005. PMID: 24709567
Wong CV, You F, Januszyk M, Gurtner GC, Kuang AA. Transcriptional Profiling of Rapamycin-Treated Fibroblasts from Hypertrophic and Keloid Scars. Ann Plast Surg. 2014 Jun;72(6):711-9. PMID: 24835866
Atashroo D, Raphel J, Chung MT, Paik KJ, Parisi-Amon A, McArdle A, Senarath-Yapa K, Zielins ER, Tevlin R, Duldulao C, Walmsley GG, Hu MS, Momeni A, Domecus B, Rimsa JR, Greenberg L, Gurtner GC, Longaker MT, Wan DC. Studies in Fat Grafting: Part II. Effects of Injection Mechanics on Material Properties of Fat. Plast Reconstr Surg. 2014 Jul;134(1):39-46. PMID: 25028817
Maan ZN, Januszyk M, Rennert RC, Duscher D, Rodrigues M, Fujiwara T, Ho N, Whitmore A, Hu MS, Longaker MT, Gurtner GC. Noncontact, Low-Frequency Ultrasound Therapy Enhances Neovascularization and Wound Healing in Diabetic Mice. Plast Reconstr Surg. 2014 Sep;134(3):402e-411e. PMID: 25158717
Maan ZN, Rennert RC, Koob TJ, Januszyk M, Li WW, Gurtner GC. Cell Recruitment by Amnion Chorion Grafts Promotes Neovascularization. J Surg Res. 2015 Feb;193(2):953-62. PMID: 25266600
Garza RM, Paik KJ, Chung MT, Duscher D, Gurtner GC, Longaker MT, Wan DC. Studies in Fat Grafting: Part III. Fat Grafting Irradiated Tissue--Improved Skin Quality and Decreased Fat Graft Retention. Plast Reconstr Surg.2014 Aug;134(2):249-57. PMID: 25068325
Tevlin R, McArdle A, Senarath-Yapa K, Wearda T, Duldulao C, Maan ZN, Hu MS, Atashroo D, Zielins ER, Paik KJ, Brunski J, Gurtner GC, Longaker MT. Key transcriptional differences exist in diabetic fracture healing. Plast Reconstr Surg. Oct 2014. PMID: 25254763
Atashroo D, Duscher D, Maan ZN, Zielins ER, Paik K, Whittam A, Lin M, McArdle A, Duldulao C, Walmsley GG, Hu MS, Tevlin R, Wan DC, Gurtner GC, Longaker MT. Adipose derived stromal cells obtained by ultrasound assisted liposuction versus suction assisted liposuction: a comparison of their regenerative capacity. Plast Reconstr Surg. Oct 2014. PMID: 25254755
Garg RK, Rennert RC, Duscher D, Sorkin M, Kosaraju R, Auerbach LJ, Lennon J, Chung MT, Paik K, Nimpf J, Rajadas J, Lonaker MT, Gurtner GC. Capillary Force Seeding of Hydrogels for Adipose-Derived Stem Cell Delivery in Wounds. Stem Cells Transl Med. 2014 Sep;3(9):1079-89. PMID: 25038246
Rennert RC, Sorkin M, Januszyk M, Duscher D, Kosaraju R, Chung MT, Lennon J, Radiya-Dixit A, Raghvendra S, Maan ZN, Hu M, Rajadas J, Rodrigues M, Gurtner GC. Diabetes Impairs the Angiogenic Potential of Adipose Derived Stem Cells by Selectively Depleting Cellular Subpopultions. Stem Cell Res Ther. 2014 Jun 18;5(3):79. PMID: 24943716
Gurtner GC, Longaker MT. Reply: Tension Shielding with the Embrace Device: Does it Really Improve Scars? Plast Reconstr Surg. 2014 Oct;134(4):664e-6e. PMID: 25357068
Than PA, Gurtner GC. Discussion: Osteoblastic Differentiation of Wharton Jelly Biopsy Specimens and their Mesenchymal Stromal Cells after Serum-Free Culture. Plast Reconstr Surg. 2014 Jul;134(1):70e-71e. PMID: 25028858
Gurtner GC. Book Review:RegenerativeMedicine Applications in Organ Transplantation. TissueEngineering, Part A. October 2014. Tissue Eng Part A. [In Press]
Maan ZN, Rodrigues M, Rennert RC, Whitmore AJ, Duscher D, Januszyk M, Hu M, Davis C, Whittam AJ, Gurtner GC. Understanding Regulatory Pathways of Neovascularization in Diabetes. Expert Reviews in Endocrinology and Metabolism. 2014 Sep;9(5):487-501
Hu M, Hong WanX, Rennert RC, Walmsley GG, Maan Z, Duscher D, McArdle A, Zimmermaan A, Chung MT, Wan DC, Lorenz P, Gurtner GC, Longaker MT. Murine Dorsal Ischemic Flap Model. JoVE. 2014. [In Press]
Januszyk M, Longaker MT, Gurtner GC. A Novel Postoperative Dressing for Scar Reduction. J of Wound Tech. 2014. [In Press]
Wong VW, Garg RK, Sorkin M, Rustad KC, Akaishi S, Levi K, Nelson ER, Tran M, Rennert R, Liu W, Longaker MT, Dauskardt RH, Gurtner GC. Loss of Keratinocyte Focal Adhesion Kinase Stimulates Dermal Proteolysis through Upregulation of MMP9 in Wound Healing. Ann Surg. 2014 Dec;260(6):1138-46. PMID: 25389925
Duscher D, Rennert RC, Januszyk M, Anghel E, Maan ZN, Whittam AJ, Perez MG, Koaraju R, Hu MS, Walmsley GG, Atashroo D, Khong S, Butte AJ, Gurtner GC. Aging Disrupts Cell Subpopulation Dynamics and Diminishes the Function of Mesenchymal Stem Cells. Sci Rep. 2014 Nov 21;4:7144. PMID: 25413454
Lim AF, Weintraub J, Kaplan EN, Januszyk M, Cowley C, McLaughlin P, Beasley B, Gurtner GC, Longaker MT. The Embrace Device Significantly Decreases Scarring following Scar Revision Surgery in a Randomized Controlled Trial. Plast Reconstr Surg 2014 Feb;133(2):398-405. PMID: 24105084
Rennert RC, Sorkin M, Wong VW, Gurtner GC. Organ-Level Tissue Engineering Using Bioreactor Systems and Stem Cells: Implications for Transplant Surgery. Current Stem Cell Research & Therapy. 2014 Jan;9(1):2-9.PMID: 24180421
Sawada H, Saito T, Nickel NP, Alastalo TP, Glotzbach JP, Chan R, Haghighat L, Fuchs G, Januszyk M, Cao A, Lai YJ, Jesus Perez V, Kim YM, Wang L, Chen PI, Spiekerkoetter E, Mitani Y, Gurtner GC, Sarnow P, Rabinovitch M. Reduced BMPR2 Expression Induces GM-CSF Translation and Macrophage Recruitment in Humans and Mice to Exacerbate Pulmonary Hypertension. J Exp Med. 2014 Feb 10;211(2):263-80. PMID: 24446489
Hu MS, Januszyk M, Hong WX, Walmsley GG, Zielins ER, Atashroo DA Maan ZN, McArdle A, Takanishi DM, Gurtner GC, Longaker MT, Lorenz HP. Gene Expression in Fetal Murine Keratinocytes and Fibroblasts. J Surg Res. 2014 Jul;190(1):344-57. PMID: 24726057
Auerbach LJ, Declerk BK, Garrison F, Gurtner GC, Auerbach PS. Poly-L-Arginine Topical Lotion Tested in a Mouse Model for Frostbite Injury. Wilderness Environ Med. 2014 Jun;25(2):160-5. PMID: 24631228
Jones GE, Neligan PC, Newman MI, Phillips BT, Sacks JM, Zenn MR. Intraoperative Laser Angiography using the SPY System: Review of the Literature and Recommendations for Use. Ann Surg Innov Res . 2013 Jan 7;7(1):1. PMID: 23289664
D’Amico Ra, Rubin JP, Neumeister MW, Del Vecchio DA, Gurtner GC, Cerderna PS, Seward W, Shoaf L. American Society of Plastic Surgeons/Plastic Surgery Foundation Regeneration Task Force: A Report of the ASPS Task Force on Regenerative Medicine: Opportunities for Plastic Surgery. Plast Reconstr Surg. 2013 Feb;131(2):393-9. PMID: 23358001
Nauta AC, Grova M, Montoro DT, Zimmermann A, Tsai M, Gurtner GC, Galli SJ, Longaker MT. Evidence that Mast Cells Are Not Required for Healing of Splinted Cutaneous Excisional Wounds in Mice. PloS ONE. 2013;8(3):e59167. PMID: 23544053
Suga H, Glotzbach J, Sorkin M, Longaker M,. Paracrine Mechanism of Angiogenesis in Adipose-derived Stem Cell Transplantation. Ann Plas Surg. 2014 Feb;72(2):234-41. PMID: 23636112
Rustad KC, Wong VW, Gurtner GC. The Role of Focal Adhesion Complexes in Fibroblast Mechanotransduction During Scar Formation Differentiation. 2013 Oct;86(3):87-91. PMID: 23623400
Momeni A, Ghaly M, Gupta D, Karanas YL, Kahn DM, Gurtner GC, Lee GK. Nipple ReconstructionAfter Implant-Based Breast Reconstruction: A “Matched-Pair” Outcome Analysis Focusing on the Effects of Radiotherapy. J Plast Reconstr Aesthet Surg. 2013 Sep;66(9):1202-5. PMID: 23664573.
Wong V, Beasley B, Zepeda J, Dauskardt R, Yock P, Longaker MT. A Mechanomodulatory Device to Minimize Incisional Scar Formation.Adv Wound Care (New Rochelle). 2013 May;2(4):185-94. PMID: 24527342
Auerbach PS, Auerbach LJ, Galvez MG, Wehner MR, Gurtner GC, Glotzbach J, Chang EI. A Novel MouseModel for Frostbite Injury. Wilderness Environ Med. 2013 Jun;24(2):94-104. PMID: 23481507
Fujiwara T, Kubo T, Kanazawa S, Shingaki K, Taniguchi M, Matsuzaki S, Gurtner GC, Tohyama M, Hosokawa K. Direct Contact of Fibroblasts with Neuronal Processes Promotes Differentiation to Myofibroblasts and Induces Contraction of Collagen Matrix In Vitro. Wound Repair Regen. 2013 Jul-Aug;21(4):588-94. PMID: 23758129.
Rennert RC, Sorkin M, Garg RK, Januszyk M, Gurtner GC. Cellular Response to a Novel Fetal Acellular Collagen Matrix: Implications for Tissue Regeneration. Int J Biomater. 2013;2013:527957. PMID: 23970899
Koob TJ, Rennert R, Zabek N, Massee M, Lim JJ, Temenoff JS, Li WW, Gurtner G. Biological Properties of Dehydrated Human Amnion/Chorion Composite Graft: Implications for Chronic Wound Healing. Int Wound J.2013 Oct;10(5):493-500. PMID: 23902526
Nauta A, Gurtner GC, Longaker MT. Adult Stem Cells in Small Animal Wound Healing Models. Methods in Molecular Biology. 1037:81-98 Sept 2013. PMID: 24029931
Wong VW, Gurtner GC, Longaker MT. Wound Healing: A Paradigm for Regeneration. Mayo Clin Proc. 2013 Sep;88(9):1022-31. PMID: 24001495
Levi B, Glotzbach GP, Sorkin M, HGyun J, Januszyk M, Wan DC, Li S, Nelson ER, Longaker MT, Gurtner GC. Molecular Analysis and Differentiation Capacity of Adipose-Derived Stem Cells from Lymphedema Tissue. Plastic Recon Surg. 2013 Sep;132(3):580-9. PMID: 23985633
Momeni A, Ghaly M, Gupta D, Karanas YL, Kahn DM, Gurtner GC, Lee G. Nipple Reconstruction: Risk Factors and Complications After 189 Procedures. Eur J Plast Surg. 2013 Oct 1;36(10):633-8. PMID: 24072956
Chung MT, Zimmermann AS, Paik KJ, Morrison SD, Hyun JS, Lo DD, McArdle A, Montoro DT, Walmsley GG, Senarath-Yapa K, Sorkin M, Rennert R, Chen HH, Chung AS, Vistnes D, Gurtner GC, Longaker MT, Wan DC. Isolation of Human Adipose-Derived Stromal Cells Using Laser-Assisted Liposuction and Their Therapeutic Potential in Regenerative Medicine. Stem Cells Transl Med. 2013 Oct;2(10):808-17. PMID: 24018794.
Januszyk , Gurtner GC. High-Throughput Single-Cell Analysis for Wound Healing Applications. 2013 Nov;2(9):457-69. PMID: 24527358
Wong VW, Martindale RG, Longaker MT, Gurtner GC. From Germ Theory to Germ Therapy: Skin Microbiota, Chronic Wounds, and Probiotics. Plast Reconstr Surg. 2013 Nov;132(5):854e-861e. PMID: 24165637
Rennert RC, Rodriguez M, Wong VW, Duscher D, Hu M, Maan Z, Sorkin M, Gurtner GC, Longaker MT. Biological Therapies for the Treatment of Cutaneous Wounds: Phase III and Launched Therapies. Expert Opin Biol Ther. 2013 Nov;13(11):1523-41. PMID: 24093722
Chen JS, Longaker MT, Gurtner GC. Murine Models of Human Wound Healing. Methods Mol Biol. 2013;1037:265-74. PMID: 24029941
Wapnir I, Dua M, Kieryn A, Paro J, Morrison D, Kahn D, Meyer S, Gurtner GC. Intraoperative Imaging of Nipple Perfusion Patterns and Ischemic Complications in Nipple-Sparing Mastectomies. Ann Surg Oncol. 2014 Jan;21(1):100-6. Epub 2013 Sep 18. PMID: 24046104
Nauta A, Seidel C, Deveza L, Montoro D, Grova M, Ko SH, Hyun J, Gurtner GC, Longaker MT, Yang F. Adipose-Derived Stromal Cells Overexpressing Vascular Endothelial Growth Factor Accelerate Mouse Excisional Wound Healing. Mol Ther. 2013 Feb;21(2):445-55. PMID: 23164936
Wong VW, Sorkin M, Gurtner GC. Enabling Stem Cell Therapies for Tissue Repair: Current and Future Challenges. Biotechnol Adv . 2013 Sep-Oct;(5):744-51. PMID:23178704
Wong VW, Longaker MT, Gurtner GC. Soft Tissue Mechanotransduction in Wound Healing and Fibrosis. Semin Cell Dev Biol. 2012 Dec;23(9):981-6. PMID: 23036529
Levi B, Nelson ER, Hyun JS, Glotzbach JP, Li S, Nauta A, Montoro DT, Lee M, Commons GC, Hu S, Wu JC, Gurtner GC, Longaker MT. Enhancement of Human Adipose-Derived Stromal Cell Angiogenesis Through Knockdown of a BMP-2 Inhibitor. Plast Reconstr Surg. 2012 Jan;129(1):53-66. PMID: 21915082
Rustad KC, Wong VW, Sorkin M, Glotzbach JP, Major MR, Rajadas J, Longaker MT, Gurtner GC. Enhancement of Mesenchymal Stem Cell Angiogenic Capacity and Stemness by a Biomimetic Hydrogel Scaffold. Biomaterials. 2012 Jan;33(1):80-90. PMID: 21963148
Garg R, Wong VW, Gurtner GC. Of Mice and Men: Mechanical Signaling and Scar Formation Across Species . Jan 2012. Issue 15, 67-68. [In Press]
Levi B, Glotzbach JP, Wong VW, Nelson ER, Hyun J, Wan DC, Gurtner GC, Longaker MT. Stem Cells: Update and Impact on Craniofacial Surgery. J Craniofac Surg. 2012 Jan;23(1):319-22. PMID: 22337434
Glotzbach JP, Wong VW, Levi B, Longaker MT, Gurtner GC. Delivery Strategies for Stem Cell-Based Therapy. J Healthcare Eng.2012 Aug; Vol 3: 1-20 [In Press]
Satterwhite T, Son J, Carey J, Zeidler K, Bari S, Gurtner GC, Chang J, Lee G,K. Microsurgery Education in Residency Training: Validating an Online Curriculum. Ann Plast Surg. 2012 Apr;68(4):410-4. PMID: 22421490
Wong VW, Levi B, Rajadas J, Longaker MT, Gurtner GC. Stem Cell Niche for Skin Regeneration. Int J Biomater. 2012;2012;926059. PMID: 22701121
Chen JS, Wong VW, Gurtner GC. Therapeutic Potential of Bone Marrow- Derived Mesenchymal Stem Cells for Cutaneous Wound Healing. Front Immunol. 2012 Jul 10;3:192. PMID: 22787462
Rustad KC, Gurtner GC. Mesenchymal Stem Cells Home to Sites of Injury and Inflammation. Advances in Wound Care. 2012 Aug;1(4):147-52. PMID: 24527296
Wong VW, Wan DC, Gurtner GC, Longaker MT. Regenerative Surgery: Tissue Engineering in General Surgical Practice. World J Surg. 2012 Oct;36(10):2288-99. PMID: 22777416
Wong VW, Gurtner G. Tissue Engineering for the Management of Chronic Wounds: Current Concepts and Future Perspectives. Exp Dermatol. 2012 Oct;21(10):729-34. PMID: 22742728
Rennert RC, Sorkin M, Garg RK, Gurtner GC. Stem Cell Recruitment After Injury: Lessons for Regenerative Medicine. Regan Med. 2012 Nov;7(6):833-50. PMID: 23164083
Longaker MT, Gurtner GC. Introduction: Wound Repair. Semin Cell Dev Biol . 2012 Dec;23(9):945. PMID: 23059792
Levi B, Hyun JS, Montoro DT, Lo DD, Chan CK, Hu S, Sun N, Lee M, Grova M, Connolly AJ, Wu JC, Gurtner GC , Weissman IL, Wan DC, Longaker MT. In Vivo Directed Differentiation of Pluripotent Stem Cells for Skeletal Regeneration. Proc Natl Acad Sci USA. 2012 Dec11;109(50):20379-84. PMID: 23169671
Wong VW, Sorkin M, Glotzback JP, Longaker MT, Gurtner GC. Surgical Approaches to Create Murine Models of Human Wound Healing. J Biomed Biotechnol. 2011. PMID: 21151647
Longaker MT, Gurtner GC: Diathermy or Surgical Scalpel for Abdominal Skin Incisions: What is the Impact on Clinical Practice? Ann Surg. 2011 Jan;253(1):14-15. PMID: 21294284
Paterno J, Vial IN, Wong VW, Rustad KC, Sorkin M, Shi Y, Bhat KA, Thangerajeh H, Glotzbach JP, Gurtner GC. Akt-mediated Machanotransduction In Murine Fibroblasts During Hypertrophic Scar Formation. Wound Repair Regen.2011 Jan-Feb;19(1):49-58. PMID: 21134033
Ko SH, Nauta A, Wong V, Glotzbach J, Gurtner GC, Longaker MT. The Role of Stem Cells in Cutaneous Wound Healing: What Do We Really Know? Plast Reconstr Surg. 2011 Jan;127 Suppl 1:10S-20S. PMID: 21200267
Januszyk M, Gurtner GC. Statistics in Medicine. Plast Reconstr Surg. 2011 Jan;127(1): 437-44. PMID: 21200241
Glotzbach JP, Wong VW, Gurtner GC, Longaker MT. Regenerative Medicine. Curr Probl Surg. 2011 Mar;48(3):148-212. PMID: 21295632
Wong VW, Rustad KC, Galvez MG, Neofyotou E, Glotzbach JP, Januszyk M, Major MR, Sorkin M, Longaker MT, Rajadas J, Gurtner GC. Engineered Pullulan-Collagen Composite Dermal Hydrogels Improve Early Cutaneous Wound Healing. Tissue Eng Part A. 2011 Mar;17(5-6):631-44. PMID: 20919949
Glotzbach JP, Wong VW, Gurtner GC, Longaker MT. In Brief: Regenerative Medicine. Curr Probl Surg. 2011 Mar;48(3):142-6. PMID: 21295631
Glotzbach JP, Januszyk M, Vial IN, Wong VW, Gelbard A, Kalisky T, Thangarajah H, Longaker MT, Quake SR, Chu G, Gurtner GC. An Information Theoretic, Microfluidic-Based Single Cell Analysis Permits Identification of Subpopulations Among Putatively Homogeneous Stem Cells. PLoS One. 2011;6(6):e21211. Epub 2011 Jun 22. PMID: 21731674
Ruidiaz ME, Messmer D, Atmodjo DY, Vose JG, Huang EJ, Kummel AC, Rosenberg HL, Gurtner GC. Comparative Healing of Human Cutaneous Surgical Incisions Created by the PEAK PlasmaBlade, Conventional Electrosurgery, and a Standard Scalpel. Plast Reconstr Surg. 2011 Jul;128(1):104-11. PMID: 21701326
Gurtner GC, Dauskardt RH, Wong VW, Bhatt KA, Wu K, Vial IN, Padois K, Korman JM, Longaker MT. Improving Cutaneous Scar Formation by Controlling the Mechanical Environment: Large Animal and Phase I Studies. Ann Surg. 2011 Aug;254(2):217-25. PMID: 21606834
Chang EI, Galvez MG, Glotzbach JP, Hamou CD, El-ftesi S, Rappleye CT, Sommer KM, Rajadas J, Abilez OJ, Fuller GG, Longaker MT, Gurtner GC. Vascular Anastomosis Using Controlled Phase Transitions in Poloxamer Gels. Nature Med. 2011 Aug 28;17(9):1147-52. PMID: 21873986
Nauta A, Gurtner GC, Longaker M. Wound Healing and Regenerative Strategies. Oral Dis. 2011 Sep;17(6):541-9. PMID: 21332599
Rappleye CT, Wong VW, Gurtner GC. Soft Tissue Adhesives - A Review. J Wound Tech. Oct(14):15-19, Oct 2011. [In Press]
Ko SH, Nauta A, Morrison SD, Zhou H, Zimmermann A, Gurtner GC, Ding S, Longaker MT. Antimycotic Ciclopirox Olamine in the Diabetic Environment Promotes Angiogenesis and Enhances Wound Healing. PLoS One. 2011;6(11). PMID: 22125629
Levi B, Glotzbach JP, Januszyk M, James A, Nelson E, Li S, Wan DC, Quarto N, Hyung J, Lee M, Commons G, Longaker MT, Gurtner GC. CD105 Protein Depletion Enhances Human Adipose-Derived Stromal Cell Osteogenesis Through Reduction of Transforming Growth Factor ß1 (TGF-ß1) Signaling. J Biol Chem. 2011 Nov 11;286(45):39497-509. PMID: 21949130
Wong VW, Rustad KC, Glotzbach JP, Sorkin M, Inayathullah M, Major MR, Longaker MT, Rajadas J, Gurtner GC. Pullulan Hydrogels Improve Mesenchymal Stem Cell Delivery into High-Oxidative-Stress Wounds. Macromol Biosci. 2011 Nov 10;11(11):1458-66. PMID: 21994074
Wong VW, Akaishi S, Longaker MT, Gurtner GC. Pushing Back: Wound Mechanotransduction in Repair and Regeneration. J Invest Dermatol. 2011 Nov;131(11):2186-96. PMID: 21776006
Levi B, Hyun JS, Nelson ER, Li S, Montoro DT, Wan DC, Jia FJ, Glotzbach JC, James AW, Lee M, Huang M,Quarto N, Gurtner GC, Wu JC, Longaker MT. Nonintegrating Knockdown and Customized Scaffold Design Enhances Human Adipose-Derived Stem Cells in Skeletal Repair. Stem Cells. 2011 Dec;29(12):2018-29. PMID: 21997852
Wong VW, Paterno J, Sorkin M, Glotzbach JP, Levi K, Januszyk M, Rustad KC, Longaker MT, Gurtner GC. Mechanical Force Prolongs Acute Inflammation via T-Cell-Dependent Pathways During Scar Formation. Faseb J. 2011 Dec;25(12):4498-510. PMID: 21911593
Wong VW, Rustad KC, Akaishi S, Sorkin M, Glotzbach JP, Januszyk M, Nelson ER, Levi K, Paterno J, Vial IN,Kuang AA, Longaker MT, Gurtner GC. Focal Adhesion Kinase Links Mechanical Force to Skin Fibrosis via Inflammatory Signaling. Nat Med. 2011 Dec 11;18(1):148-52. PMID: 22157678
Spiotto MT, Banh A, Papandreou I, Cao H, Galvez MG, Gurtner GC, Denko NC, Le QT, Koong AC. Imaging the Unfolded Protein Response in Primary Tumors Reveals Microenvironments with Metabolic Variations that Predict Tumor Growth. Cancer Res. 2010 Jan 1;70(1):78-88.PMID: 20028872
Thangarajah H, Vial IN, Grogan RH, Yao D, Shi Y, Januszyk M, Galiano RD, Chang EI, Galvez MG, Glotzbach JP, Wong VW, Brownlee M, Gurtner GC. HIF-1alpha Dysfunction in Diabetes. Cell Cycle.2010 Jan 1;9(1):75-9, PMID: 20016290
Glotzbach J, Wong, VW, Gurtner GC. Neovascularization in Diabetes. Expert Review of Endocrinology & Metabolism 5: 99-111, 2010. [In Press]
Wong VW, Gurtner GC. Discussion. Construction and Clinical Application of a Human Tissue-Engineered Epidermal Membrane. Plast Reconstr Surg. 2010 Mar;125(3):910-2. PMID: 20195118
Komorowska-Timek E, Gurtner GC. Intraoperative Perfusion Mapping with Laser-Assisted Indocyanine Green Imaging Can Predict and Prevent Complications in Immediate Breast Reconstruction. Plast Reconstr Surg. 2010 Apr;125(4):1065-73. PMID: 20335859
Fong KD, Hu D, Eichstadt S, Gupta DM, Pinto M, Gurtner GC, Longaker MT, Lorenz HP. The SNaP System: Biomechanical and Animal Model Testing of a Novel Ultraportable Negative-Pressure Wound Therapy System. Plast Reconstr Surg. 2010 May;125(5):1362-71. PMID: 20440156
Komorowska-Timek, E, Gurtner GC, Lee GK. Supercharged Reverse Pedicle Anterolateral Thigh Flap in Reconstruction of a Massive Defect: A case report. Microsurgery. 2010 Jul;30(5):397-400. PMID: 20238382
Roldan JC, Detsch R, Schaefer S, Chang E, Kelantan M, Waiss W, Reichert TE, Gurtner GC, Deisinger U. Bone Formation and Degradation of a Highly Porous Biphasic Calcium Phosphate Ceramic in Presence of BMP-7, VEGF and Mesenchymal Stem Cells in an Ectopic Mouse Model. J Craniomaxillofac Surg. 2010 Sep;38(6):423-30. PMID: 20189819
Rustad KC, Sorkin M, Levi B, Longaker MT, Gurtner GC. Strategies for Organ Level Tissue Engineering Organogenesis. 2010 Jul-Sep;6(3):151-7. PMID: 21197216
Wong VW, Rustad KC, Longaker MT, Gurtner GC. Tissue Engineering in Plastic Surgery: A Review. Plast Reconstr Surg. 2010 Sep;126(3):858-68. PMID: 20811219
Behr B, Ko SH, Wong VW, Gurtner GC, Longaker MT. Stem Cells. Plast Reconstr Surg. 2010 Oct;126(4):1163-71. PMID: 20555302
Glotzback JP, Levi B, Wong VW, Longaker MT, Gurtner GC. The Basic Science of Vascular Biology: Implications for the Practicing Surgeon. Plast Reconstr Surg. 2010 Nov;126(5):1528-38. PMID: 21042110
Roldan JC, Chang E, Kelantan M, Jazayeri L, Deisinger U, Detsch R, Reichert TE, Gurtner GC. Quantifying Migration and Polarization of Murine Mesenchymal Stem Cells on Different Bone Substitutes by Confocal Laser Scanning Microscopy. J Craniomaxillofac Surg. 2010 Dec;38(8):580-8. PMID: 20189818
Longaker M, Gurtner GC. Meta Analysis of the Effectiveness of Surgical Scalpel or Diathermy in Making Abdominal Skin Incisions. Ann Surg. Dec 2010 PMID: 21135686
Rohde C, Howell BW, Buncke GM, Gurtner GC, Levin LS, Pu LL, Levine JP. A Recommended Protocol for the Immediate Postoperative Care of Lower Extremity Free-Flap Reconstructions. J Reconstr Microsurg. 2009 Jan;25(1):15-9. PMID: 18979418
Gurtner GC, Longaker MT. Topical Lineage-Negative Progenitor-Cell Therapy for Diabetic Wounds. Plast Reconstr Surg. 2009 Jan;123(1):421-3. PMID: 19116584
Thangarajah H, Vial IN, Chang E, El-Ftesi S, Januszyk M, Chang El, Paterno J, Neofytou E, Longaker MT, Gurtner GC. Adipose Stromal Cells Adopt a Proangiogenic Phenotype Under the Influence of Hypoxia. Stem Cells. 2009 Jan;27(1): 266-74. PMID: 18974212
El-Ftesi S, Chang El, Longaker MT, Gurtner GC. Aging and Diabetes Impair the Neovascular Potential of Adipose-Derived Stromal Cells. Plast Reconstr Surg. 2009 Feb;123(2):475-85. PMID: 19182604
Loh S, Chang EI, Galvez MG, Thangarajah H, El-ftesi S, Vial IN, Lin DA, Gurtner GC. SDF-1 Alpha Expression During Wound Healing in the Aged is HIF Dependent. Plast Reconstr Surg. 2009 Feb;123(2 Suppl):65S-75S.PMID: 19182665
Levine S, Garfein ES, Weiner H, Yaremchuk MJ, Saadeh PB, Gurtner GC, Levine JP, Warren SM. Intracranial Microvascular Free Flaps. J Reconstr Microsurg. 2009 Feb;25(2):89-95. PMID: 18925548
Hamou C, Callaghan M, Thangarajah H, Chang E, Chang EI, Grogan RH, Paterno JM, Vial I, Jazayeri L, Gurtner GC. Mesenchymal Stem Cells Can Participate in Ischemic Neovascularization. Plast Reconstr Surg. 2009 Feb;123(2 Suppl):45S-55S. PMID: 19182663
Chang EI, Bonillas RG, El-Ftesi S, Chang E, Ceradini DJ, Vial IN, Chan DA, Michaels J 5th, Gurtner GC. Tissue Engineering Using Autologous Microcirculatory Beds as Vascularized Bioscaffolds. FASEB J. 2009 Mar;23(3):906-15. PMID: 19001054
Hopper RA, VerHalen JP, Tepper O, Mehrara BJ, Detch R, Chang EI, Baharestani S, Simon BJ, Gurtner GC. Osteoblasts Stimulated with Pulsed Electromagnetic Fields Increase HUVEC Proliferation via a VEGF-A Independent Mechanism. Bioelectromagnetic. 2009 Apr;30(3):189-197. PMID: 19194859
Ghali S, Bhatt K, Dempsey M, Jones DM, Singh S, Aarabi S, Butler PE, Gallo RL, Gurtner GC. Treating Chronic Wound Infections with Genetically Modified Free Flaps. Plast Reconstr Surg. 2009 Apr;123(4):1157-68. PMID: 19337084 (Winner of 2010 James Barrett Brown Award)
Orgill DP, Manders EK, Sumpio BE, Lee RC, Attinger CE, , Ehrlich HP. The Mechanisms of Action of Vacuum Assisted Closure: More to Learn. Surgery. 2009 Jul;146(1):40-51. PMID: 19541009
Thangarajah H, Yao D, Chang E, Shi Y, Jazayeri L, Vial IN, Galiano RD, Du XL, Grogan R, Galvez M, Januszyk M, Brownlee M, Gurtner GC. The Molecular Basis for Impaired Hypoxia-Induced VEGF Expression in Diabetic Tissues. Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13505-10. PMID: 19666581
Gurtner GC, Rohrich RJ, Longaker MT. From Bedside to Bench and Back Again: Technology Innovation in Plastic Surgery. Plast Reconstr Surg. 2009 Oct;
Sen CK, Gordillo GM, Roy S, Kirsner R, Lambert L, Hunt TK, Gottrup F, Longaker MT. Human Skin Wounds: A Major and Snowballing Threat to Public Health and the Economy. . 2009 Nov-Dec;17(6):763-71, Dec 2009. PMID: 19903300
Loh SA, Carlson GA, Chang EI, Huang E, Palanker D, Gurtner G. Comparative Healing of Surgical Incisions Created by the PEAK PlasmaBlade, Conventional Electrosurgery, and a Scalpel.Comparative Study. 2009 Dec;124(6):1849-59. PMID: 19952641
Callaghan MJ, Chang EI, Seiser N, Aarabi S, Ghali S, Kinnucan E, Simon B, Gurtner GC. Pulsed Electromagnetic Fields Accelerate Normal and Diabetic Wound Healing by Increasing Endogenous FGF-2 Release. Plastic Reconstr Surg. 2008 Jan;121(1):130-41. PMID: 18176216
Ghali S, Dempsey MP, Jones DM, Grogan RH, Butler PE, Gurtner GC. Plastic Surgical Delivery Systems for Targeted Gene Therapy. Ann Plast Surg. 2008 Mar;60(3):323-32. PMID: 18443515
5.Ceradini DJ, Yao D, Grogan RH, Callaghan MJ, Edelstein D, Brownlee M, Gurtner GC. Decreasing Intracellular Superoxide Corrects Defective Ischemia-Induced New Vessel Formation in Diabetic Mice.J Biol Chem. 2008 Apr 18;283(16):10930-8. PMID: 18227068
Jazayeri L, Callaghan MJ, Grogan RH, Hamou C, Thanik V, Ingraham CR, Capell BC, Pelo CR, Gurtner GC. Diabetes Increases p53-Mediated Apoptosis Following Ischemia. Plast Reconstr Surg. 2008 Apr;121(4):1135-43. PMID: 18349630
Gurtner GC, Werner S, Barrandon Y, Longaker MT. Wound Repair and Regeneration. Nature. 2008 May 15;453(7193):314-21. PMID: 18480812
Dempsey MP, Hamou C, Michaels J 5th, Ghali S, Jazayeri L, Grogan RH, Gurtner GC. Using Genetically Modified Microvascular Free Flaps to Deliver Local Cancer Immunotherapy with Minimal Systemic Toxicity. Plast Recon Surg. 2008 May;121(5):1541-53. PMID:18453976 (Winner of 2009 James Barrett Brown Winner)
Gurtner GC, Chang E. Priming Endothelial Progenitor Cells: A New Strategy to Improve Cell Based Therapeutics. Arterioscler Thromb Vasc Biol. 2008 Jun;28(6):1034-5. PMID: 18495972
Aarabi S, Draper L, Grayson B, Gurtner GC. Bisphosphonate-Associated Osteonecrosis of the Jaw: Successful Treatment at 2-Year Follow-Up. Plast Reconstr Surg. 2008 Aug;122(2):57e-9e. PMID: 18626318
Le H, Kleinerman R, Lerman OZ, Brown D, Galiano R, Gurtner GC, Warren SM, Levine JP, Saadeh PB. Hedgehog Signaling is Essential for Normal Wound Healing. Wound Repair Regen. 2008 Nov-Dec;16(6):768-73. PMID: 19128247
Callaghan MJ, Longaker MT, Gurtner GC. Progress and Potential for Regenerative Medicine. Annu Rev Med. 2007;58:299-312. PMID: 17076602
Capla JM, Grogan RH, Callaghan MJ, Galiano RD, Tepper OM, Ceradini DJ, Gurtner GC. Diabetes Impairs Endothelial Progenitor Cell-Mediated Blood Vessel Formation in Response to Hypoxia. Plast Reconstr Surg. 2007 Jan;119(1):59-70. PMID: 17255657
Singh SP, Chang EI, Gossain AK, Mehara BJ, Galiano RD, Jensen J, Longaker MT, Gurtner GC, Saadeh PB. Cyclic Mechanical Strain Increases Production of Regulators of Bone Healing in Cultured Murine Osteoblasts. J Am Coll Surg. 2007 Mar;204(3):426-34. PMID: 17324777
Ghali S, Butler PE, Tepper OM, Gurtner GC. Vascular Delay Revisited. Plast Reconstr Surg. 2007 May;119(6):1735-44. PMID: 17440348
Aarabi S, Longaker MT, Gurtner GC. Hypertrophic Scar Formation Following Burns and Trauma: New Approaches to Treatment.PLoS Med. 2007 Sep;: PMID: 17803351
Egger M, Schgoer Wk, Beer AG, Jeschke J, Leierer J, Theurl M, Frauscher D, Tepper OM, Niederwanger A, Ritsch A, Kearney M, Wanschitz J, Gurtner GC, Fisher-Colbrie R, Weiss G, Piza-Katzer H, Losordo DW, Patsch JR, Schratzberger P, Krichmaier R. Hypoxia Up-Regulates the Angiogenic Cytokine Secretoneurin via an HIF-1alpha- and Basic FGF Dependent Pathway in Muscle Cells. FASEB J. 2007 Sep;21(11):2906-17. PMID: 17504977
Michaels J 5th, Churgin SS, Blechman KM, Grieves MR, Aarabi S, Galiano RD, Gurtner GC. Db/db Mice Exhibit Severe Wound-Healing Impairments Compared to Other Murine Diabetic Strains in a Silicone-Splinted Excisional Wound Model.Wound Repair Regen. 2007 Sep-Oct;15(5):665-70. PMID: 17971012
Aarabi S, Bhatt KA, Shi Y, Paterno J, Chang EI, Loh SA, Holmes JW, Longaker, Yee H, Gurtner GC. Mechanical Load Initiates Hypertrophic Scar Formation Through Decreased Cellular Apoptosis.FASEB J. 2007 Oct;21(12):3250-61.PMID: 17504973
Kleinman ME, Greives MR, Churgin SS, Blechman K, Chang EI, Ceradini DJ, Tepper OM, Gurtner GC. Hypoxia-induced Mediators of Stem/Progenitor Cell Trafficking are Increased in Children with Hemangioma. Vasc Biol. 2007 Dec;27(12):2664-70.PMID: 17872454
Bhatt KA, Chang EI, Seiser N, Warren S, Lin SE, Bastidas N, Ghali S, Thibboneire A, Capla J, McCarthy JG, Gurtner GC. Uniaxial Mechanical Strain: An In Vitro Correlate to Distraction Osteogenesis. J Surg Res. 2007 Dec;143(2):329-36
Chang EI, Loh S, Ceradini DJ, Chang EI, Lin SE, Aarabi S, Bastidas N, Chan DA, Freedman ML, Giaccia AJ, Gurtner GC. Age Decreases Endothelial Progenitor Cell Recruitment Through Decreases in hypoxia-inducible factor 1alpha Stabilization During Ischemia.Circulation. 2007 Dec 11;116(24):2818-29.PMID: 18040029
Chang EI, Chang EI, Thangarajah H, Hamou C, Gurtner GC. Hypoxia, Hormones, and Endothelial Progenitor Cell in Hemangioma Lymphat Res Biol. Lymphat Res Biol. 2007;5(4):237-3. PMID: 18370914
Capla JM, Ceradini DJ, Tepper OM, Callaghan MJ, Bhatt KA, Galiano RD, Levine JP, Gurtner GC. Skin Graft Vascularization Involves Precisely Regulated Regression and Replacement of Endothelial Cells through Both Angiogenesis and Vasculogenesis. Plast Reconstruc Surg. 2006 Mar;117(3):836-44. PMID: 16525274
Michaels J, Levine JP, Hazen A, Ceradini DJ, Galiano RD, Soltanian H, Gurtner GC. Biologic Brachytherapy: Ex Vivo Transduction of Microvascular Beds for Efficient Targeted Gene Therapy. Plast Reconstruc Surg2006 Jul;118(1):54-65; discussion 66-8. PMID: 16816674
Gold LI, Rahman M, Blechman KM, Greives MR, Churgin S, Michaels J, Callaghan MJ, Cardwell NL, Pollins AC, Michalak M, Siebert JW, Levine JP, Gurtner GC, Nanney LB, Galiano RD, Cadacio CL. Overview of the Role for Calreticulin in the Enhancement of Wound Healing Through Multiple Biological Effects.J Investig Dermatol Symp Proc. 2006 Sep;11(1):57-65. PMID: 17069011
Pittman KM, Losken HW, Kleinman ME, Marcus JR, Blei F, Gurtner GC, Marchuk DH. No Evidence for Maternal-Fetal Microchimerism in Infantile Hemangioma: A Molecular Genetic Investigation. Journal of Investigative Dermatology 2006 Nov;126(1):2533-8. PMID: 16902414
Krummel TM, Gertner M, Makower J, Milroy C, Gurtner GC, Woo R, Risking DJ, Binyamin G, Conner JA, Mery CM, Shafi BM, Yock PG. Inventing Our Future: Training the Next Generation of Surgeon Innovators. Seminars Pediatric Surgery. 2006 Nov;15(4):309-18. PMID: 17055962
Ceradini DJ, Gurtner GC. Homing to Hypoxia: HIF-1 as a Mediator of Progenitor Cell Recruitment to Injured Tissue.Trend Cardiovas Med. 2005 Feb;15(2):57-63. PMID: 15885571
Kleinman ME, Blei F, Gurtner GC. Circulating Endothelial Progenitor Cells and Vascular Anomalies. Lymphatic Research and Biology. 2005;3(4):234-9. PMID: 16379593
Derderian CA, Bastidas N, Lerman OZ, Bhatt KA, Lin SE, Voss J, Holmes JW, Levine JP, Gurtner GC. Mechanical Strain Alters Gene Expression in an In Vitro Model of Hypertrophic Scarring. Ann Plast Surg. 2005 Jul;55(1):69-75; discussion 75. PMID: 15985794
Rowe NM, Michaels J 5th, Soltanian H, Dobryansky M, Peimer C, Gurtner GC. Sonographically Guided Percutaneous Carpal Tunnel Release: An Anatomic and Cadaveric Study. Ann Plast Surg. 2005 Jul;55(1):52-6; discussion 56. PMID: 15985791
Cetrulo CL Jr, Knox KR, Brown DJ, Ashinoff RL, Dobryansky M, Ceradini DJ, Capla JM, Chang EI, Bhatt KA, McCarthy JG Gurtner GC. Stem Cells and Distraction Osteogenesis: Endothelial Progenitor Cells Home to the Ischemic Generate in Activation and Consolidation. Plastic Reconstruc Surg. 2005 Sep 15;116(4):1053-64; discussion 1065-7. PMID: 16163094
Michaels J 5th, Dobryansky M, Galiano RD, Bhatt KA, Ashinoff R, Ceradini DJ, Gurtner GC. Topical Vascular Endothelial Growth Factor Reverses Delayed Wound Healing Secondary to Angiogenesis Inhibitor Administration. Wound Repair Regen. 2005 Sep-Oct;13(5):506-12. PMID: 16176459
Callaghan MJ, Ceradini DJ, Gurtner GC. Hyperglycemia-Induced Reactive Oxygen Species and Impaired Endothelial Progenitor Cell Function. Antioxid Redox Signal. 2005 Nov-Dec;7(11-12):1476-82. PMID: 16356110
Park S, Tepper OM, Galiano RD, Capla JM, Baharestani S, Kleinman ME, Pelo CR, Levine JP, Gurtner GC. Selective Recruitment of Endothelial Progenitor Cells to Ischemic Tissues with Increased Neovascularization. Plast Reconstr Surg. 2004 Jan;113(1):284-93. PMID: 14707648
Derderian CA, Gurtner GC, McCarthy JG. Reconstruction of a Large Mandibular Defect Utilizing Temporary Zygomatic-Ramal Fixation and Bilateral Risdon Incisions. J Craniofac Surg. 2004 Jan;15(1):16-9. PMID: 14704555
Dobryansky M, Galiano RD, Cetrulo CL, Bhatt KA, Michaels J, Ashinoff R, Levine JP, Gurtner GC. Endostatin Inhibits Ischemia-Induced Neovascularization and Increases Ischemic Tissue Loss. Ann Plast Surg. 2004 May;52(5):512-8. PMID:15096942
Michaels J 5th, Dobryansky M, Galiano R, Ceradini DJ, Bonillas R, Jones D, Seiser N, Levine JP, Gurtner GC. Ex Vivo Transduction of Microvascular Free Flaps for Localized Peptide Delivery. Ann Plast Surg. 2004 Jun;52(6):581-4. PMID: 15166989
Ashinoff RL, Cetrulo CL, Galiano RD, Dobryansky M, Bhatt KA, Ceradini DJ, Michaels J 5th, McCarthy JG, Gurtner GC. Bone Morphogenic Protein-2 Gene Therapy for Mandibular Distraction Osteogenesis. Ann Plast Surg. 2004 Jun;52(6):585-90 discussion 591. PMID: 15166991
S, Steinmetz HG, Gurtner GC. Topical Vascular Endothelial Growth Factor Accelerates Diabetic Wound Healing Through Increased Angiogenesis and by Mobilizing and Recruiting Bone Marrow-Derived Cells. AM J Pathol. 2004 Jun;164(6):1935-47. PMID: 15161630
Galiano RD, Michaels J 5th, Dobryansky M, Levine JP, Gurtner GC. A Quantitative and Reproducible Murine Model of Excisional Wound Healing. Wound Repair Regen. 2004 Jul-Aug;12(4):485-92. PMID: 15260814
Ceradini DJ, Kulkarni AR, Callaghan MJ, Tepper OM, Bastidas N, Galiano RD, Gurtner GC. Progenitor Cell Trafficking is Regulated by Hypoxic Gradients through HIF-1 Induction of SDF-1. Nat Med. 2004 Aug;10(8):858-64. PMID: 15235597
Tepper OM, Callaghan MJ, Chang EI, Galiano R, Bhatt KA Baharestani S, Gan J, Simon B, Hopper RA, Levine JP, Gurtner GC. Electromagnetic Fields Increase In Vitro and In Vivo Angiogenesis Through Endothelial Release of FGF-2. The Faseb Journal. 2004 Aug;18(11):1231–3, Epub 2004 Jun 18. PMID: 15208265
Lerman OZ, Galiano RD, Armour M, Levine JP, Gurtner GC. Cellular Dysfunction in the Diabetic Fibroblast: Impairment in Migration, Vascular Endothelial Growth Factor Production, and Response to Hypoxia. AM J Pathol. 2003 Jan;162(1):303-12. PMID: 12507913
Chung S, Hazen A, Levine JP, Baux G, Olivier WA, Yee HT, Margiotta M, Karp NS, Gurtner GC. Vascularized Acellular Dermal Matrix Island Flaps for the Repair of Abdominal Muscle Defects. Plast Reconstr Surg. 2003 Jan;111(1):225-32. PMID: 12496583
Tepper OM, Kalka G, Galiano RD, Gurtner GC. Endothelial Progenitor Cells: The Promise of Vascular Stem Cells for Plastic Surgery. Plast Reconstr Surg. 2003 Feb;111(2):846-54. PMID: 12560713
Olivier WA, Hazen, A, Soltanian H, Levine JP, Chung S,Gurtner GC. Reliable Assessment of Skin Flap Viability Using Orthogonal Polarization Imaging. Plast Reconstr Surg. 2003 Aug;112(2):547-55. PMID: 12900613
Dederian CA, Olivier WA, Baux G, Levine JP, Gurtner GC. Microvascular Free-Tissue Transfer for Traumatic Defects of the Upper Extremity: A 25-year Experience. J Reconstr Microsurg. 2003 Oct;19(7):455-62. PMID: 14634908
Kleinman ME, Tepper OM, Capla JM, Bhatt KA, Ceradini DJ, Galiano RD, Blei F, Levine JP, Gurtner GC. Increased Circulating AC133+ CD34+ Endothelial Progenitor Cells in Children with Hemangioma. Lymphat Res Bio. 2003;1(4):301-7. PMID: 15624558
2002 Publications:
Tepper OM, Galiano RD, Capla JM, Kalka C, Gagne PJ, Jacobowitz GR, Levine JP, Gurtner GC: Human Endothelial Progenitor Cells from Type II Diabetics Exhibit Impaired Proliferation, Adhesion, and Incorporation into Vascular Structures. Circulation. 2002 Nov 26;106(22):2781-6. PMID: 12451003
2001 Publications:
Newman LA, Kuerer HM, McNeese MD, Hunt KK, Gurtner GC, Vlastos GS, Robb G, Singletary SE: Reduction Mammoplasty Improves Breast Conservation Therapy in Patients with Macromastia. Am J Surg. 2001 Mar;181(3):215-20. PMID: 11376574
Patrick CW Jr., Zheng B, Wu X, Gurtner GC, Barlow M, Koutz C, Chang DW, Schmidt M, Evans GRD: Muristerone A - Induced Nerve Growth Factor Release from Genetically Engineered Human Dermal Fibroblasts for peripheral nerve tissue engineering. Tissue Eng. 2001 Jun;7(3):303-11. PMID: 11429150
2000 Publications:
Gurtner GC, Evans GR: Advances in Head and Neck Reconstruction. Plast Reconstr Surg. 2000 Sep;106(3):672-82. PMID: 10987478
1999 Publications:
Gurtner GC, Longaker MT: Genetically Modified Fibroblasts Induce Angiogenesis in the 3x6 cm Rat Epigastric Island Flap: Commentary. European Journal of Plastic Surgery. 22: 209-211, 1999. [In Press]
1997 Publications:
Spragg DD, Afford DR, Greferath R, Larsen CE, Lee KD, Gurtner GC, Cybulsky MI, Tosi PF, Nicolau C, Gimbrone MA Jr: Immunotargeting of Liposomes to Activated Vascular Endothelial Cells: A Strategy for Site-Selective Delivery in the Cardiovascular System.PNAS.1997 Aug 5;94(16):8795-800. PMID: 9238057
1995 Publications:
Gurtner GC, Davis V, Li H, McCoy M, Sharpe A, Cybulsky MI: Targeted Disruption of the Murine VCAM1 Gene: Essential Role of VCAM-1 in Chorioallantoic Fusion and Placentation. Genes Dev. 1995 Jan 1;9(1):1-14.PMID: 7530222
Robertson CS, Chung SC, Ling TK, Ip SM, Li AK, Gurtner GC: Effect of Carbon Dioxide Pneumoperitoneum on Bacteremia and Endotoxemia in an Animal Model of Peritonitis. Br J Surg. 1995 Jun:82(6):844-8. PMID: 7627528
1994 Publications:
Robertson CS, Chung SCS, Li AKC, Gurtner GC: Two Team Synchronous Esophagectomy. Br J Surg. 1994 Nov;81(11):1620-2. PMID: 7827888
1989 Publications:
Palinski W, Rosenfeld ME, Yla-Herttuala,Gurtner GC, Socher SS, Butler S, Parthasarathy S, Carew TE, Steinberg S, Witztum J: Low Density Lipoprotein Undergoes Oxidative Modification In Vivo. Proc Natl Acad Sci U S A. 1989 Feb;86(4):1372-6. PMID: 2465552
1988 Publications:
Hall TS, Borkon AM, Gurtner GC, Brawn J, Hutchins GM, Reitz BA, Baumgartner WA: Improved Static Lung Preservation with Corticosteroids and Hypothermia. J Heart Transplant. 1988 Sep-Oct;7(5):348-52. PMID:3199247