Berryman et al. Publishes Paper in Journal of Investigative Dermatology Highlighting Role of Mechanotransduction in Fibrosis and Wound Healing

Dr. Katharina Berryman, Dr. Geoffrey C. Gurtner, and Dr. Kellen Chen report a new study in the Journal of Investigative Dermatology highlighting the role of mechanotransduction in wound healing and fibrosis. The study identifies key fibroblast subpopulations that respond to mechanical cues and drive divergent healing outcomes, linking biomechanical signaling to both regeneration and scarring. These findings further support targeting mechanotransduction pathways, such as FAK signaling, as a promising strategy to improve tissue repair and reduce fibrosis.

https://doi.org/10.1016/j.jid.2026.02.027

Congratulations to Katharina S. Berryman, Abdelrahman M. Alsharif, Mansi Singh, Filiberto Quintero, Amelia B. Knochel, Maria Gracia Mora Pinos, Dharshan Sivaraj, Lulejeta Latifi, Fidel Jr. Saenz, Pedro Mora Pinos, Andrew C. Hostler, Javier Gonzalez, Ben Litmanovich, Sultana M. Mojadidi, Jonathan P. Yasmeh, Hudson Kussie, Maisam S. Jafri, Autumn Lester, William W. Hahn, Maia Granoski, Geoffrey C. Gurtner, and Kellen Chen on this publication advancing the understanding of wound healing biology.